The kidneys of people with sickle cell disease do not concentrate urine

The kidneys of people with sickle cell disease do not

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The kidneys of people with sickle cell disease do not concentrate urine properly, which results in poor control of bodily fluids. Additional fluids are given to try and slow or stop the sickling process which should reduce the amount and duration of pain. Fluids may be given in many ways, but orally or intravenously are most common. Fluids should be given with care so as to prevent fluid overload which may in turn cause adverse events such as heart failure or fluid building up in the lungs (Okomo.2017). Okomo U, Meremikwu MM. Fluid replacement therapy for acute episodes of pain in people with sickle cell disease. Cochrane Database of Systematic Reviews 2017, Issue 7. Art. No.: CD005406. DOI: 10.1002/14651858.CD005406.pub5 1. Thalassemia is a blood disorder passed down through families in which the body makes an abnormal form or inadequate amount of hemoglobin. Hemoglobin is the protein in red blood cells that carries oxygen. The disorder results in large numbers of red blood cells being destroyed, which leads to anemia. It occurs when there is a defect in the gene making alpha globin and beta globin for our hemoglobin. For chronic management it can be treated with blood transfusion, nutritional supplements and even a bone marrow transplant (Thalassemia.2010).
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Thalassemia: MedlinePlus Medical Encyclopedia. (2010). Retrieved from
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  • Spring '16
  • Sickle-cell disease, blood disorder

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