B high dose intravenous immunoglobulin ivig can be

Info icon This preview shows pages 438–449. Sign up to view the full content.

b) High dose intravenous immunoglobulin (IVIg) can be initiated c) Plasmapheresis can be done d) High dose intravenous immunoglobulins and plasmapharesis are equally effective 438
Image of page 438

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Management of Guillain Barre Syndrome:- Supportive care is extremely important in Guillain-Barre syndrome (GBS) since up to 30 percent of patients develop neuromuscular respiratory failure requiring mechanical ventilation. - In addition, severe autonomic dysfunction occurs in about 20 percent and warrants intensive care unit (ICU) monitoring. 439
Image of page 439
Disease modifying treatment:- The main modalities of therapy for Guillain-Barre syndrome (GBS) include : 1. - Plasma exchange (also called plasmapheresis) 2. - Administration of intravenous immune globulin (IVIG). 440
Image of page 440

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Plasmapheresis:- With plasma exchange there is early improvement in muscle strength and reduced needfor mechanical ventilation and better recovery. Intravenous immune globulin :- IVIG is as effective as plasma exchange for the treatment of GBS. Patients with more severe clinical disease may benefit from longer duration of IVIG treatment. 441
Image of page 441
All of the following statements regarding treatment of GBS are true, except – (NBE/DNB Pattern) a) Corticosteroids may be used for early recovery and prevent long hospital stay b) High dose intravenous immunoglobulin (IVIg) can be initiated c) Plasmapheresis can be done d) High dose intravenous immunoglobulins and plasmapharesis are equally effective A 442
Image of page 442

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

POLIO MYELITIS 443
Image of page 443
Which of the following is LEAST suggestive of infection with polio virus - (AIIMS Nov 99) a) Low grade fever and malaise with complete resolution in 2 to 3 days b) Biphasic illness with several days of fever, then meningeal symptoms and asymmetric flaccid paralysis 5 to 10 days later c) Descending motor paralysis with preservation of tendon reflexes and sensation d) Failure to isolate a virus from the cerebrospinal fluid in the presence of marked meningismus 444
Image of page 444

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Clinical manifestations of poliomyelitis: i) Asymptomatic - 95% cases of poliovirus infection remain asymptomatice. ii) Abortive polio - • About 5% ofpatients presents with this form . Presents with, fever, headache, sorethroat, nausea, vomiting • Meningitis and other neurological manifestations are absent • Spontaneous resolution occurs. iii) Non Paralytic form of polio:- . The patient gives features of abortive polio along with meningitis ( aseptic meningitis) iv) Paralytic polio:- . Seen in only about 1% of poliovirus infection. 445
Image of page 445
446
Image of page 446

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

An interesting feature of poliovirus infection is that it has been readily isolated from C.N.S. tissue of fatal cases but can rarely be recovered from the C.S.F during clinical disease. . This is in contrast to the closely related coxsackie, echo and picornaviruses which have been isolated frequently from the C.S.F. 447
Image of page 447
Which of the following is LEAST suggestive of infection with polio virus - (AIIMS Nov 99) a) Low grade fever and malaise with complete resolution in 2 to 3 days
Image of page 448

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Image of page 449
This is the end of the preview. Sign up to access the rest of the document.
  • Winter '16
  • jean grey

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern