hematuria ddx infectious UTI hemorrhagic cystitis Trauma Heme causes SCD TCP

Hematuria ddx infectious uti hemorrhagic cystitis

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hematuria ddx infectious: UTI, hemorrhagic cystitis Trauma Heme causes: SCD, TCP Metabolic cause: hypercalcemia Structural: tumor, obstruction, stones, vascular malformations Glomerular; Bergers, HSP, PSG, alports 236. Proteinuria defn >100mg/m2/day pathologic 237. Classification of proteinuria Benign transient proteinuria: inc protein w/ vig exercise, fever, dehydration, CHF Orthostatic proteinuria: inc urinary protein while upright, but not supine. Pathologic protineuria: glomeular disease or tubular disease(interstitia nephritis, ischemic renal injuryATN) and nephrotoxic drugs 238. nephrotic syndrome heavy proteinuria Edema hypercholesterolemia 239. Nephritic syndrome gross hematuria HTN Fluid overload from renal insufficiency 240. MCC of acute glomerulonephritis? MCC of chronic GN? Acute: PSGN Chronic: IgA nephropathy
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241. CF PSGN 8-14 d after skin or pharynx w/ nephritogenic strian of GABHS. 28 days after impetigo. Hematuria(gross), proteinuria, HTN, fluid overload. Low complement 242. Dx of PSGN ASO titer ADB titer UA, serum complement, renal US, RFTs, serum albumin, serum cholesterol 243. Tx of PSGN. Does abx help dec risk of PSGN? Rheumatic fever? Fluid restriction, antihypertensive, dietary restrictions of protein, sodium, potassium, phosphorous. Abx tx doesn't reduce risk of PSGN but will reduce risk of rheumatic fever 244. IgA nephropathy Etio: CF: Dx: tx: Etio: abnl clearance or formation of IgA Immune complexes CF: recurrent gross hematuria assoc w/ resp infections. Transient ARF. Microscopic hematuria Dx: renal biopsy Tx: suportive, ACEI, steroids, immunosuppressants 245. HSP nephritis Defn CF Defn: IgA mediated vaculitis w/ nonTCP palpable purpura on buttocks+thighs, abd pain, arthritis, gross or microscopic hematuria. CF: Protineuria presnt possible glomerular inflammation should do renal bx. In majority renal features self limited-recover in 3 mo. 246. Nephrotic syndrome defn heavy proteinuria(>50mg/kg/24hours), hypoalbuminemia, hypercholesterolemia, edema 247. Categories of Nephrotic syndrome PRimary NS: 90% of all childhood cases. MCC of primary is MCD NS from other primary glomerular diseases: IgA nephropathy, MPGN, PSGN NS that results from systemic diseases: SLE, HSP 248. CF of nephrotic syndrome Edema which follows a URI. PRedisposed to thromboses Inc risk of encapsulated org infections-can have SBP, PNA, sepsis 249. Dx of Nephrotic syndrome
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UA: shows +3/4 protein, elevated CBC CMP: met acidosis. BUN/Cr C3, ANA, Antistrep ab Renal US 250. massive edema with nephrotic syndrome IV infusions of 25% albumin to achieve a diuresis and maintain intravascular volume 251. MCD tx steroids, no added salt. Steroid resistant-cyclophosphamide, cyclosporine 252. HUS defn ARF in presence of MHA, TCP Two different subtypes: Shiga toxin assoc HUS, Atypical HUS 253. CF of HUS diarrheal prodrome-->sudden onset of hemolytic anemia, TCP, ARF 254. Alports syndrome progressive hereditary nephritis Type IV collagen defect X linked dominant.
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