Most common around 60 years old zoster virus can

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Most common around 60 years old, zoster virus can react, causing new disease called shinglesPrevention is possible with injections of inactivated VZ virus in chickenpox vaccineFigure 6.7 Chickenpox. Caused by infection with the varicella-zoster virus, the trademark phenotype of chickenpox is the small, itchy, fluid-filled blisters that can form anywhere on the body.
ShinglesShingles (aka herpes zoster) is due to reactivation of varicella-zoster virus (VZV)Because VZV lies dormant in inactive nerve cells, its reactivation typically results in painful blistersoHowever, unlike initial chickenpox rash, blisters are localized and limited to small areasFirst symptom is usually severe pain, tingling, or burning localized where rash will later presentoOnce red patches form into small blisters, it is possible for individuals to infect someone who has not been previously exposed to VZVThus, someone who has neither (1) previously had chickenpox, nor (2) been administered VZV vaccine is susceptible to being exposed to and developing chickenpox (not Shingles) from person during contagious stage of their shingles outbreakPatients with mild symptoms can be treated with OTC pain medications, while those with increasingly painful blisters can be treated with anti-viral drug, acyclovirFigure 6.8 Shingles.Reactivation of the varicella-zoster virus may result in painfully localized blisters limited to small areas.SmallpoxSmallpox (aka variola virus) was a linear, double-stranded, enveloped DNA virus about 186,000 nucleotides longTwo (2) variants to smallpox virus: variola major and variola minor
oVariola major was classified as more severe and most common manifestation of the diseaseSmallpox was highly contagious – it was easily transmitted through the air as well as through contact with an infected individualoIn both cases, infection was characterized by an initial high fever followed by rashin mouth or throat, as this was often point of entryoRash would then appear externally on face and then begin spreading downwardsto arms and legs and eventually to hands and feetRash became raised bumps filled with thick, opaque fluid that would eventually form scabsOnce scabs fell off, it often left marks on skin resembling pitted scarsVirus has been globally eradicatedoOnce a major cause of death in the world, vaccine was developed in 1796 by Edward JenneroGlobal vaccination has prevented smallpox from appearing in humans since October 26, 1977, making smallpox the first infectious disease ever to be eradicatedFigure 6.9 Smallpox. Caused by the variola major virus, the raised bumps filled with a thick, opaque fluid that would eventually form scabs as shown on a child’s arm and shoulder.6.5 Viruses in Microbiology IIPolioPolio (aka poliomyelitis) is a single-stranded, non-enveloped RNA virus about 7,700 nucleotides long
oPoliovirus belongs to family of viruses called PicornaviridaeViral particle is only about 30 nm in diameter and is often considered most significant small virus

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