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17 Heart and Circulation V

Cardiac factors high heart rate and high

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Cardiac Factors : High heart rate and high contractility, caused by high sympathetic tone, Vascular Factors : High total peripheral resistance, caused by high sympathetic tone and high plasma [angiotensin II] Coupling Factors : High preload caused by high blood volume
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Antihypertensive Drugs Based on the Renin-Angiotensin System (From: Heart 93: 1026-1033, 2007)
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Baroreceptor Reflex
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Locations of Arterial Baroreceptors
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Effect of Changing Mean Arterial Pressure on Baroreceptor Action Potential Frequency
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Neural Components of the Arterial Baroreceptor Reflex
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Baroreceptor Reflex (Negative Feedback) (+) Vagus (-) Sympathetic Tone HR HR, Contractility, TPR (-) Carotid and Aortic Baroreceptors Sensors Cardiovascular Center Controller Effectors BP Regulated Variable Negative Feedback
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Standing-Squatting-Standing Test of Baroreceptor Reflex (From: Autonomic Neurosc Basic Clin 162: 3-9, 2011) Stand Squat Stand Systolic Blood Pressure Diastolic Blood Pressure Mean Blood Pressure Pulse Pressure Heart Rate Baroreceptor Reflex
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Physiological Significance of Baroreceptor Reflex Function : Minimize sudden changes in blood pressure in daily activities such as standing up Fast Adapation : Baroreceptor reflex adapts to prolonged change in blood pressure, and is therefore NOT a cause of hypertension Clinical Note
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