Acute infections cause an excess of WBCs known as ___
leukocytosis
______________.
A deficiency of WBCs, called ___
leukopenia
__, can also indicate a variety of infections including
AIDS.
What is leukemia?
Overproduction of abnormal white blood cells that have cancerous traits
Granulocytes
:
Why is this group called granulocytes?
These are granules that are observed in their cytoplasm when they have particular stains
Neutrophils:
Neutrophils have _
red
____-staining fine cytoplasmic granules and a __
multi
__-lobed nucleus;
they comprise most of the leukocytes.
What is their function?
Phagocytize viruses, fungi, and bacteria.
What does diapedesis mean?
The squeezing of cells in blood vessel walls
Eosinophils:
Eosinophils have coarse granules that stain deep __
red
_____, a ___
bi
_______-lobed nucleus.
What are their functions?
Defend against particular parasites, moderate allergic reactions
Basophils:
Basophils have fewer granules that stain __
blue
_______________.
Basophils produce chemicals, what are the functions of these chemicals?
(i)
heparin-
an anticoagulant, inhibits thrombin by enhancing the activity of
anthithrombin
(ii)
histamine-
Inflammatory chemical that acts like a vasodilator, like allergies.
4

Agranulocytes
:
Why are they called agranulocytes?
They do not have cytoplasmic granules
Monocytes:
Monocytes are the ___
largest
___ blood cells, have __
oval
______-shaped nuclei.
What is the function of the monocytes?
They phagocytize cellular debris and bacteria
Lymphocytes:
Lymphocytes are long-lived, have a large, __
spherical
____ nucleus.
What is their function?
Immunity response
Platelets
= thrombocytes
:
Blood platelets are fragments of big cells called __
megakaryocytes
_______________________.
Platelets help repair damaged blood vessels by _____
adhering
___________ to their broken edges.
Plasma:
Plasma is the clear, straw-colored fluid portion of the blood.
Plasma is mostly _
water
___________________ but contains a variety of substances.
What are plasma’s functions?
Transports gases and nutrients, regulates electrolyte and fluid balance in the blood, and maintains
the acid base balance.
Plasma proteins:
The plasma proteins are the most abundant dissolved substances in the plasma
.
Briefly describe the functions of the following plasma proteins.
albumin:
maintains the correct osmotic red of the plasma
globulin:
the transport of lipid and fat soluble vitamin, some are antibodies
5

fibrinogen:
a glycoprotein that helps in the formation of blood clots
hormones:
regulates and controls physiological functions
Other Plasma Components:
Nutrients and Gases
What are the two most important blood gases?


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- Winter '14
- red blood cells, white blood cell