3. Start non-specific calming medications, e.g. benzodiazepines, antipsychotics. 4. Start specific mood-stabilisers or relapse prevention agents, preferably when the person is able to consent to longer-term therapy. 5. Hypnotic/sedative use should be considered appropriate as a night of sleep deprivation is likely to escalate any manic patient to a higher degree of mania. 6. Any co-morbid substance misuse must also be tackled, as recovery is poorer in people with a history of substance abuse.