rats exposed to DDT develop fewer liver tumors than unexposed rats not shown in

Rats exposed to ddt develop fewer liver tumors than

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-rats exposed to DDT develop fewer liver tumors than unexposed rats, not shown in humans (exposed to DDT, rats generate detoxicating enzymes that will detoxicate other substances) - possible triggering of disease in future, maybe cancer -Berkele Public Health Institute (women under 14 yrs of age during heaviest DDT exposure, blood levels of DDT found to correlate with future breast cancer risk) -Long Island Study (no relationship between breast cancer and blood levels of DDT, blood samples taken after cancer diagnosed) - no compelling evidence of breast cancer and DDT link - malathion (insecticide) interferes with enzyme system in body (high dose can kill) -dozens of regulations to get through the pesticide market with specific instruction Video3 -Pesticide Risks, Real and Imagined - nocebo (if someone thinks they will be harmed, they will feel worse) -India, children eat food with pesticides, mixed in food, died - monocrotophos (1.2g potential for lethal dose) -pesticide exposure may lead to illness (occupational exposure) -Incidence of Parkinson higher with those exposed to pesticide -1980s drug users in California (paralyzed, parkinsons) - China White, product made by drug chemist, side product that destroys cells that produce dopamine - shortage of dopamine equals parkinsons -similar chemically to pesticide known as paraquat , - Rotenone extracted from roots of Derris plant (natural) -linked to parkinsons, because similar structure to paraquat -associations are never cause and effect -Use of pest control services at any time 1yr before birth to 3 years from birth, significantly increased risk of childhood leukemia (no risk with outdoor pesticides) (indoor spraying, when kids were young) (association) -long term effects of pesticides (food that has trace amounts) (subtle chronic effects) -pesticides can disrupt hormones ( atrazine, pesticide affect tadpols ) -pesticides can affect male hormones -similar in women, pesticide exposure linked to increased uterus and endometriosis risk -pesticide use and menstrual cycle characteristics high (premenopausal women link high) -but not cause and effect (only correlation) -soy, hummus, milk, naturally occurring estrogens (hard to see pesticides having effect on endochrine system) -3mil pesticide poisoning 220,000 death (mostly used for suicide)
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Video 4 -Herbicide used more potent so used less (application rates of teaspoons per acre) -lower toxicitidy because it interacts with enzymes in weeds not found in ppl -17 mil pounds less use per year than racemic metolachlor ((S)-Metolachlor) -mirror image isomer (more adept at killing pesticide) - colony collapse disorder (kill of bees (used for pollination) - neonicotinoids (correlated to destruction of bees, eliminated in EU) -maybe not insectides responsible?(bees infected with viruses colony colapse disorder) -natural pesticides ( nicotine, coffee leaf (unleashes weaponry against fungus, ingest chemical weapons)) -over 1000 compounds in coffee 10mg of suspected or known carcinogens -consume 1.5g of natural pesticides a day (99.9% of pesticides is natural) -body handles synthetic and natural pesticides9 the same way
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