-rats exposed to DDT develop fewer liver tumors than unexposed rats,
not shown in humans (exposed to DDT, rats generate detoxicating enzymes that will
detoxicate other substances)
-
possible triggering of disease in future, maybe cancer
-Berkele Public Health Institute (women under 14 yrs of age during heaviest
DDT exposure, blood levels of DDT found to correlate with future breast cancer risk)
-Long Island Study (no relationship between breast cancer and blood levels of
DDT, blood samples taken after cancer diagnosed)
-
no compelling evidence of breast cancer and DDT link
-
malathion (insecticide) interferes with enzyme system in body (high dose can kill)
-dozens of regulations to get through the pesticide market with specific instruction
Video3
-Pesticide Risks, Real and Imagined
-
nocebo
(if someone thinks they will be harmed, they will feel worse)
-India, children eat food with pesticides, mixed in food, died
-
monocrotophos
(1.2g potential for lethal dose)
-pesticide exposure may lead to illness (occupational exposure)
-Incidence of Parkinson higher with those exposed to pesticide
-1980s drug users in California (paralyzed, parkinsons)
-
China White,
product made by drug chemist, side product that destroys cells that
produce dopamine
-
shortage of dopamine equals parkinsons
-similar chemically to pesticide known as
paraquat
,
-
Rotenone
extracted from roots of Derris plant
(natural)
-linked to parkinsons, because similar structure to
paraquat
-associations are never cause and effect
-Use of pest control services at any time
1yr before birth to 3 years from birth,
significantly increased risk of childhood leukemia (no risk with outdoor pesticides)
(indoor spraying, when kids were young) (association)
-long term effects of pesticides (food that has trace amounts) (subtle chronic effects)
-pesticides can disrupt hormones (
atrazine, pesticide affect tadpols
)
-pesticides can affect
male hormones
-similar in women, pesticide exposure linked to increased
uterus and endometriosis
risk
-pesticide use and menstrual cycle characteristics high (premenopausal women
link high)
-but not cause and effect (only correlation)
-soy, hummus, milk, naturally occurring estrogens (hard to see pesticides having effect on
endochrine system)
-3mil pesticide poisoning 220,000 death (mostly used for suicide)
Video 4
-Herbicide used more potent so used less (application rates of teaspoons per acre)
-lower toxicitidy because it interacts with enzymes in weeds not found in ppl
-17 mil pounds less use per year than racemic metolachlor ((S)-Metolachlor)
-mirror image isomer (more adept at killing pesticide)
-
colony collapse disorder
(kill of bees (used for pollination)
-
neonicotinoids
(correlated to destruction of bees, eliminated in EU)
-maybe not insectides responsible?(bees infected with viruses
colony colapse
disorder)
-natural pesticides (
nicotine, coffee leaf
(unleashes weaponry against fungus, ingest chemical
weapons))
-over 1000 compounds in coffee 10mg of suspected or known carcinogens
-consume
1.5g
of natural pesticides a day (99.9% of pesticides is natural)
-body handles synthetic and natural pesticides9 the same way
