Found in large airways to the lungs and in large

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Found in large airways to the lungs and in large arteries,internal eye muscles that adjust pupil size -. Gap junctions and depolarizations are rare I. Consist of muscle fibers = independent II. Richly supplied w/nerve endings III. Responds to neural stimulation w/grade contractions . Unitary and multi-unit smooth muscle = innervated by autonomic (involuntary) & responds to hormones.
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Excitation-contraction coupling Also known as E-C coupling = transmission of AC along sarcolemma causes myofilaments to slide. Causes rise in intracel levels of Ca ions - allow filaments to slide 1. Nerve impulses reaches: axon terminal & opens voltage gated Ca = Ca entry triggers release of ACh 2. Release ACh binds tO Ach receptors = opening gated Na+K+ channels (*Greater influx of Na+ causes voltage change 3. Local depolarization opens voltage gated Na channels = allows more Na to enter further depolarize, generating and propagating Ap. 4. Transmission of Ap along T-tubules = changes shape of proteins in turn stimulate SR Ca release channels to release Ca.
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  • Fall '08
  • CARNEGIE
  • muscle tension

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