Which of the following is NOT TRUE a Partition coefficient of hydrophilic drug

Which of the following is not true a partition

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61.Which of the following is NOT TRUE?a.Partition coefficient of hydrophilic drug is greater than that of lipophilic drugsb.Active absorption of drugs is subject to competitive inhibition between structurally related compoundsc.The Henderson-Hasellbalch equation gives relation between pH, pKa and degree of ionization62.The following statements about non-electrolytes are true EXCEPT:63.For a weakly acidic drug, the extent of ionization is greater at a pH less than pKa of the drug64.A female patient has consumed large quantity of aspirin tablets. The pH of her urine is 4.5. What percent of aspirin is present in the unionized form if pKa of aspirin is 3.5?65.Transdermal drug delivery systems have the advantage of bypassing the first-pass effecta. Trueb. False66.Water-soluble drugs are encapsulated in the inner compartment of liposomes67.Which of the following is FALSE regarding osmotic pump drug delivery system?
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68.Which of the following drugs is appropriate for incorporation into an oral extended release dosage form?69.The transdermal DDS "TransdemScop" is used for--------a.Hypertension, once weeklyb.Chronic pain relief for 72 hoursc.Post-menopausal symptomsd.Nausea/vomiting motion sickness70.Two acids HA1 and HA2 have pKa of 9.2 and 4.7 respectively. This would imply that…71.The concentration of a drug solution is 50 mg/mL and the molecular weight is300. The molarity of this solution is…72.pKa of the weak acid fenoprofen is 4.5. Calculate the percent ionized state ata pH of 6.5
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73.Which of the following is the weakest acid/ (pKa values are given in brackets)a.Citric acid (4.74)b.Aspirin (3.50)c.Lactic acid (3.86)d.Carbonic acid (6.37)
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