Serotonin blockers 1 dolasetron anzemet 2 granisetron

Serotonin blockers
1. dolasetron (Anzemet)
2. granisetron (Kytril)
3. ondansetron (Zofran)
4. palonosetron (Aloxi)
These drugs are used for...
What type/class of drugs do they belong to?
A patient with terminal cancer has not had
chemotherapy for a few weeks and has had no
nausea or vomiting since then. However, he is
taking dronabinol twice a day. The reason for the
dronabinol order is to
Used for nausea and vomiting associated with
chemotherapy, and anorexia associated with weight
loss in AIDS patients
A patient is 2 months pregnant. She comes to the
clinic complaining of severe morning sickness. She
has tried numerous non-pharmacologic measures to
relieve the morning sickness, but they have not
worked. The nurse anticipates the use of which
antinausea drug?
A. phosphorated carbohydrate solution (Emetrol)
Rationale: Phosphorated carbohydrate solution (Emetrol)
is a mint-flavored, pleasant-tasting oral solution used to
relieve nausea. It works by direct local action on the walls
of the GI tract, where it reduces cramping caused by
excessive smooth muscle contraction. It can be used to
control mild cases of nausea and vomiting. It does not
have a pregnancy category rating, but one of its listed
unlabeled (non-FDA-approved) uses is for treatment of
morning sickness during pregnancy. The other drugs are
not indicated for use in pregnancy.
- Mint-flavored oral solution
- Used off label for treatment of morning sickness
phosphorated carbohydrate solution (Emetrol)
- Used for the prevention of nausea and vomiting
associated with highly emetogenic cancer
chemotherapy regimens
aprepitant (Emend)