Question 25
1 out of 1 points
A patient has been prescribed a histamine-2 (H
2
) receptor antagonist for the treatment of
GERD. Why are H
2
RAs more effective than H
1
receptor antagonists in the treatment of
diseases of the upper GI tract?
Response
Feedback:
H
2
RAs block the effect of histamine at H
2
receptors, particularly those in
the parietal cells of the stomach. Antihistamines that block histamine-1 (H
1
)
receptors, the most frequent site of action for antihistamines, do not affect H
2
receptor sites, and H
2
RAs do not block H
1
sites. H
1
sites are not prevalent
in the GI tract. Both classes of drugs may be administered orally.

Question 26
1 out of 1 points
A woman with an inflammatory skin disorder has begun taking prednisone in an effort to
control the signs and symptoms of her disease. The nurse who is providing care for this
patient should prioritize which of the following potential nursing diagnoses in the
organization of the patient's care?
Response
Feedback:
Treatment with glucocorticoids such as prednisone is associated with
numerous adverse effects, including the risk for excess fluid volume.
Constipation and impaired gas exchange are not among the most common
adverse effects and CNS effects are normally limited to anxiety, mood
swings, and insomnia rather than acute confusion.
Question 27
1 out of 1 points
Prior to administering a dose of 5-FU to a patient with pancreatic cancer, the nurse is
conducting the necessary drug research. The nurse is aware that 5-FU is a cell cycle–specific
chemotherapeutic agent. Which of the following statements best describes cell cycle–
specific drugs?
Response
Feedback:
Chemotherapeutic drugs that are most effective during a particular phase of
the cycle are known as cell cycle– (or cell phase) specific, whereas drugs
that act independently of a specific cell cycle (or cell phase) are cell cycle–
nonspecific. Not all cell cycle–specific drugs achieve a synergistic effect
with cell cycle–nonspecific drugs. These drugs are not named because of the
particular sequence of cytotoxic events that they cause.
Question 28
1 out of 1 points
A patient develops diarrhea secondary to antibiotic therapy. He is to receive two tablets of
diphenoxylate HCl with atropine sulfate (Lomotil) orally as needed for each loose stool. The
nurse should inform him that he may experience
Response
Feedback:
The most common adverse effects of diphenoxylate HCl with atropine
sulfate are drowsiness and dizziness related to the drug's chemical similarity
to meperidine, an opioid. Tachycardia is an adverse effect, not bradycardia.
Muscle aches and an increase in appetite are not adverse effects of the drug.
Question 29

1 out of 1 points
Mr. Tan is a 69-year-old man who prides himself in maintaining an active lifestyle and a
healthy diet that includes adequate fluid intake. However, Mr. Tan states that he has
experienced occasional constipation in recent months. What remedy should be the nurse's
first suggestion?


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- Summer '15
- Pharmacology, Irritable bowel syndrome, Ulcerative colitis, Helicobacter pylori