Of transport vesicle and culminates with membrane

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of transport vesicle and culminates with membrane fusion between vesicle and target membrane3. Membrane fission is carried out by coat complexes, targeting by Rab GTPases and fusion by SNARE complexes4. ER to Golgi transport is a key component of the biosynthetic pathway that delivers newly synthesized proteins and lipids to other parts of the cell5. The Golgi is able to sort and target cargo for lysosomes and cargo for exocytosis6. The endocytic pathway balances exocytosis by uptake of plasma membrane and extracellular cargo, which is either recycled and transport to lysosomes for degradation

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