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Copyright © 2015. F.A. Davis Company Parkinson’ s Disease Destruction of Substantia Nigra Decreased Dopamine Production Relative Excess of Acetylcholine Impairment of Semiautomatic Movements
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Copyright © 2015. F.A. Davis Company Parkinson’ s Disease Etiology Unknown Genetic Certain Drugs Encephalitis
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Copyright © 2015. F.A. Davis Company Parkinson’ s Disease Signs and Symptoms Muscular Rigidity Bradykinesia Changes in Posture Pill-Rolling Tremor Difficulty Initiating Movement Shuffling and Freezing Gait
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Copyright © 2015. F.A. Davis Company Parkinson’ s Disease Signs and Symptoms (cont’d)
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Copyright © 2015. F.A. Davis Company Symptoms of ANS Dysfunction Diaphoresis Constipation Orthostatic Hypotension Drooling Dysphagia Seborrhea Frequent Urination
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Copyright © 2015. F.A. Davis Company Parkinson’ s Disease Diagnosis History Physical Examination MRI
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Copyright © 2015. F.A. Davis Company Parkinson’ s Disease Therapeutic Interventions Anticholinergic Agents Dopamine Agonists Monoamine Oxidase B Inhibitors COMT Inhibitors Pallidotomy Deep Brain Stimulation
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Copyright © 2015. F.A. Davis Company Parkinson’ s Disease Nursing Diagnoses Impaired Physical Mobility Self-Care Deficit Risk for Injury Diagnoses for Dementia
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Copyright © 2015. F.A. Davis Company Huntington’ s Disease Pathophysiology/Etiology Genetic Autosomal Dominant Degeneration of Parts of Brain
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Copyright © 2015. F.A. Davis Company Huntington’ s Disease Signs and Symptoms Dementia Personality Changes Inappropriate Behavior Paranoia Violence Choreiform Movements Dysphagia Depression Death
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Copyright © 2015. F.A. Davis Company Huntington’ s Disease Signs and Symptoms (cont’d)
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Copyright © 2015. F.A. Davis Company Huntington’ s Disease Diagnosis Family History MRI CT Genetic Testing/Counseling
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Copyright © 2015. F.A. Davis Company Huntington’ s Disease Therapeutic Interventions Antipsychotics Antidepressants Antichorea Agents Stem Cell Transplants
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Copyright © 2015. F.A. Davis Company Alzheimer’ s Disease Pathophysiology Progressive Degenerative DIsease Neurofibrillary Tangles Neuritic Plaques
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Copyright © 2015. F.A. Davis Company Alzheimer’ s Disease Etiology Unknown May be Genetic Down’s Syndrome
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Copyright © 2015. F.A. Davis Company Alzheimer’ s Disease Signs and Symptoms Stage 1 Increasing Forgetfulness Stage 2 Progressive Memory Loss Irritability Depression Aphasia Sleep Disruption Hallucinations Seizures
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Copyright © 2015. F.A. Davis Company Alzheimer’ s Disease Signs and Symptoms (cont’d) Stage 3 Complete Dependency Bowel and Bladder Control Lost Emotional Control Lost Inability to Recognize Significant Others Death
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Copyright © 2015. F.A. Davis Company Alzheimer’ s Disease Diagnosis History Physical Examination MRI PET, SPECT Autopsy
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Copyright © 2015. F.A. Davis Company
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