Difficult for drug to find virus without injuring normal cells Each antiviral

Difficult for drug to find virus without injuring

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Difficult for drug to find virus without injuring normal cells Each antiviral drug specific to one particular virus Antiviral agents decrease the reproduction of viruses inside the host cell but cannot destroy the virus. Effective only against actively repliacting viruses, not against those in the latent stage
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Antiviral Therapy Use drugs with extreme caution with preexisting renal or hepatic disease Judicious use is warranted during pregnancy Emphasize compliance with antiviral therapy Some drugs cause GI distress and should be taken with food
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Acyclovir
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Herpes Simplex Virus- 1
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Herpes Zoster Virus/Shingles
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Herpes Zoster (Shingles) Herpes zoster or shingles is caused by varicella-zoster virus in adults. Appears years after the primary infection of varicella or chickenpox, which usually occurs in childhood. Affects one cranial nerve or one dermatome on one side of the body. Neuralgia or pain continues after the lesions disappear. Visual impairment has resulted
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Reye’s Syndrome The cause of Reye’s syndrome has not yet been fully determined, but it is linked to a viral infection, such as influenza, in young children that have been treated with aspirin (ASA). Pathologic changes occur in the brain and the liver. Cerebral edema develops leading to increased ICP. Progresses to acute renal failure.
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Herpesviruses Causes repeated blister-like lesions on the skin, genitals, and other mucosal surfaces Antiviral drugs can lower the frequency of acute herpes episodes and diminish the intensity of the acute disease
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A patient has been diagnosed with genital herpes and has been started on oral acyclovir (Zovirax). What should be included in the teaching instructions for the patient? Select all that apply. A. Increase fluid intake up to 2 L per day B. Report any dizziness, tremors or confusion to you HCP C. Decrease the amount of fluids taken so that the drug can be more concentrated to be more effective D. Take the drug only when having the most itching or pain form the outbreak E. Use barrier methods such as condoms for sexual activity
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The patient with acute herpes zoster is prescribed oral acyclovir (Zovirax), an antiviral medication. Which statement by the patient indicates the patient needs more medication teaching? A. “I am so glad this medication will cure my shingles” B. “I will have to take the pill five times a day” C. “I should take this medication for 7-10 days” D. “If the shingles get near my eyes, I will call my HCP”
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The use of aspirin in children is limited due to the possibility of: A. Munchausen’s syndrome B. Guillain-Barre syndrome C. Angelman’s syndrome D. Reye’s syndrome
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Pathophysiology Of HIV Caused by an RNA virus or retrovirus Replication goes as follows: HIV GP 120 and GP41 to CD4 cell receptor Viral core empties into cell Reverse transcriptase copies RNA into double stranded DNA Integration of viral DNA into host DNA w/aid of integrase Using integrated DNA as blueprint, makes new viral proteins Translation of viral messenger RNA to create polyprotein Protease cleaves the strand Assembly and release of new virus
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