32 1211 The role of transcription factors in regulating gene expression General

32 1211 the role of transcription factors in

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32 12.11 The role of transcription factors in regulating gene expression General transcription factors TBP - TATA binding protein TAF - TBP associated factors
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33 12.13 DNA sites involved in regulating transcription Regulating transcription from the rat PEPCK gene
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ChIP: Global search for transcription factor binding sites 34 12.13 DNA sites involved in regulating transcription
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35 12.15 Transcriptional activators: Enhancers, Promoters, Co-activators A survey of the means by which transcriptional activators bound at distant sites can influence gene expression
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36 12.15 Transcriptional activators: Enhancers, Promoters, Co-activators Co-activators that alter chromatin structure Location of histone modifications in the chromatin of transcribed genes (yeast)
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37 12.17 Transcriptional activation Transcriptional activation model
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38 12.17 Transcriptional repression Transcriptional repression model
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39 Why?
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40 10.14 The genetic basis of ‘Being human’ Duplication of the amylase gene during human evolution: chimp (top; single copy) and human (bottom; multiple copy)
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41 10.9 Diseases that result from expansion of the trinucleotide repeats
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42 THANK YOU! Yogita Jethmalani
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