Solution of the structure of dna model building gave

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solution of the structure of DNA, model building gave a foundation of what DNA may be like, using data from previous experiments. X-ay crystallography, gave the huge clues to solving the structure, and gave evidence/confirmed, which models were right and which were incorrect. 11. Previous to Watson and Cricks presentation of the structure of DNA, Pauling and Corey proposed that DNA consisted of 3 intertwined strands. 12. Watson and Crick proposed against this theory because some of the van der Waals distances were too small and they were missing 13. hydrogen bonds. 14. They propose a double helix that is antiparallel, with 3’-5’ linkage
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15. They talk about the high water concentration and how it would be dangerous if the water levels were to drop. 16. They identify the purines and pyrimidine, and explain their pairing system. 17. There are 4 types of nucleotides- adenine, thymine, guanine, and cytosine; in a DNA helix, adenine and thymine pair together, as guanine and cytosine pair together. They are made of three elements, phosphate, sugar, and a nitrogenous base; sugar and phosphate make up the backbone of DNA. 18. Chargaff's rules states that DNA from any cell of all organisms should have a 1:1 ratio of pyrimidine and purine bases and, more specifically, that the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine. 19. It told which nitrogenous bases connected together in the helix. 20. Photo 51 provided Watson and crick with critical information; the purines and pyrimidine were stacked on top of each other, it have measurements on the diameter of DNA and the distance between bases, and evidence of a double helix. 21. When Wilkins found photo B which he later showed to Watson and Crick he found it labeled with “51”. 22. Yes, I think photo 51 was crucial to solving the structure of DNA. It provided 23. crucial information, being that DNA is made up of a double helix that I feel wouldn’t have been figured out without Franklin’s photo 51.
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