●
injection site reactions (pain,
swelling and redness)
●
mild fever.
●
shivering.
●
fatigue.
●
headache.
●
muscle and joint pain.
screening all vaccine
recipients for
contraindications and
precautions prior to
administering
immunizations. A
history of anaphylactic
reaction to a previous
vaccine, HIV infection,
Guillain-Barré
syndrome, or a
hematopoietic stem
cell transplant are
some of the
circumstances that
might contraindicate
certain vaccines. A
history of an allergy to
eggs
-any allergic rxns
Hepatitis B
To prevent HBV
transmitted sexually,
injections
-anaphylaxis
-fever
Immune Globulin
Preparations
-for Rh negative pts
exposed to Rh
positive blood
Prevent production of anti-Rh
antibodies, ↑platelet counts in ITP
pts
-disseminated intravascular coagulation
-intravascular hemolysis
-anemia
-to prevent
future Rh
positive infants
-assess VS
-monitor for hemolysis
(back pain, shaking,
chills, fever)
Immunostimulant
s
stimulate the immune
system by inducing
activation or
increasing activity of
any of its components
-necessary for organ
transplants
activation of specific white blood cells
that produce proteins of inflammation
called cytokines
-infections
-uncontrolled bleeding
-report any
fevers, chills,
back pain, and
fatigue
-avoid sharp
objects
-frequent
handwashing

Ibuprofen (Advil)
-Primary drugs to treat
mild to moderate
inflammation
-COX 1 inhibitor
-analgesic;
Inhibits prostaglandin synthesis
-primary use for musculoskeletal
disorders, mild to moderate pain,
reduction of fever, primary
dysmenorrheal pain
-RF, GI bleeding, anaphylaxis, metabolic
acidosis, hepatic impairment, nausea,
heartburn, epigastric pain, dizziness
-take with food
-ETOH
increases
stomach
irritation
-may cause
drowsiness/dizzi
ness
-report black-red
odorous stools
-Monitor VS and pain
level
-Monitor BUN, serum
creatinine, CBC w/
differential,
electrolytes, bleeding
time, and LFT
periodically
Prednisone
corticosteroids
-suppress histamine &
prostaglandins
-can inhibit immune
system
(lymphocytes/phagocy
tes) to reduce
inflammation
-suppression of adrenal gland
-metabolized to an active form of
glucocorticoid
-hyperglycemia, mood changes,
cataracts, peptic ulcers, electrolyte
imbalance, osteoporosis
-Cushing’s
-do not stop
abruptly
-discontinue gradually
-keep low dose
-use alternate day
dosing
Acetaminophen
(Tylenol)
To relieve pain and
reduce fever, no anti-
inflammatory actions
To reduce fever by direct action at level
of hypothalamus and dilation of
peripheral blood vessels (enables
sweating and dissipation of heat)
-possible liver damage
, causes less GI
irritation than aspirin, does not affect
blood coagulation
-report s/s
anemia
-affects liver long term

