In patients suffering from CVS, there is consensus that
application of preventive medication and medication
capable of aborting an episode reduces the intensity and
frequency of cycles [1], [3], [4]. Amitriptyline, propranolol,
sumatriptane are recommended preventive medications
[1], [3], [4]. Metoclopramide, ondansetron, lorazepam or
oxycodone, ideally with application at the onset of pro-
dromal symptoms, can abort an episode [1], [3], [4].
Psychosocial care is of additional benefit [1], [3], [4].
In patients who refuse cessation of cannabis use and
especially in patients who do not sufficiently respond to
cannabis use cessation alone, adopting the therapeutic
regime of CVS might be beneficial. But there is no data
supporting a potential benefit of applying the therapeutic
strategy of CVS to CHS in these patients.
Follow-up of CVS and CHS
Reliable long-term follow up data (minimum follow up
time: 12 months) of patients suffering from CVS or CHS
is sparse [1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11],
[13], [14], [15]. Differentiation between CVS and CHS is
simple in patients who do not practise chronic marijuana
abuse [1], [2]. Distinguishing between CVS from CHS in
patients who practise chronic marijuana abuse can be
extremely difficult [1], [3], [5], [9], [11].
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GMS German Medical Science 2017, Vol. 15, ISSN 1612-3174
Blumentrath et al.: Cannabinoid hyperemesis and the cyclic vomiting syndrome ...
