o A chemical incompatibility involves the degradation of the drug resulting

O a chemical incompatibility involves the degradation

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o A chemical incompatibility involves the degradation of the drug resulting from a chemical reaction. o Therapeutic incompatibility occurs within the patient as the result of two concurrently administered drugs that interact. If there is a question about compatibility, review drug inserts and drug information texts and consult with a pharmacist. o Then fill the syringe with the appropriate volume of air and inject the air into vial B. Without removing the needle from vial B, invert the vial and syringe and withdraw the required volume of medication into the syringe. Withdraw the needle from vial B and then reinsert it into vial A. Invert vial A carefully, and withdraw the required volume of medication, using caution to avoid drawing more than you need because you will be unable to inject any of it back into the vial now that the two medications are mixed. Replace the filter needle with an appropriate needle to be used for injection. The syringe then contains a mixture of medications from vials A and B. o single-dose vials= Instill air in each vial and then withdraw medication from one vial and then the second vial. There is no need to protect the needle from contact with the first medication. MIXING MEDICATIONS FROM PREFILLED SYRINGES. o Medications from prefilled syringes may also be mixed. There are two ways to perform the task: both medications can be drawn into a separate syringe, or the second medication can be drawn into the prefilled cartridge if there is adequate room. o The first method is to draw the medication from the prefilled cartridge into a separate syringe. The end of the prefilled cartridge has a plastic adapter that may have its own attached needle, or it may be designed so that a needle can be attached to it. For this method, apply gentle pressure to the entire plastic adaptor, bending it sideways, and it will slide easily off the end of the prefilled cartridge, exposing a rubber stopper at the end of the cartridge. o Cleanse the stopper with an alcohol wipe and then pierce the stopper with a hypodermic needle attached to a syringe, withdrawing the medication from the cartridge into the syringe. If the second medication is in a single-dose vial, first clean the vial stopper with alcohol. Pull into the same syringe
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a volume of air equal to the volume of medication to be withdrawn from the second medication vial. Insert the syringe needle into the vial and instill the air. Now withdraw the correct volume of medication into the syringe with the first medication, where they mix. o To mix both medications in the cartridge, place the cartridge in the plastic holder, retain the amount of air in the cartridge that will need to be instilled into the second medicine vial, and expel any excess air over that amount from the cartridge. Wipe the vial stopper with an alcohol wipe, then invert the vial prior to piercing the vial stopper with the needle on the prefilled cartridge. Hold the syringe with the first medication in a vertical position, with the needle tip pointing up. This allows air
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  • Fall '19
  • Syringe

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