Above are illustrated the critical segments of

Question
5

Above are illustrated the critical segments of precursor mRNA sequence that are
involved in spliceosome mediated RNA splicing. Which two nucleotides are joined by
the first transesterification reaction in the first step of the splicing mechanism?
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c and d
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a and e
x
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b and c
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a and c
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a and b
Question
6
Which of the following statements about alternative splicing are true?
Question
7
Hydrophobic residues located at precisely interspaced intervals aligned
along an extended α-helical region which are responsible for homo-

and heterodimerisation are characteristic of which transcription factor
(s)?
More than one answer may be correct, so you may select multiple responses. You
will lose partial credit for each incorrect response selected, and gain partial credit
for each correct response selected.
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all dimeric transcription factors
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zinc finger transcription factors
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Gal4
x
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leucine zippers transcription factors
x
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HLH transcription factors
Question
8
Poly(A) polymerase is required for the formation of the poly(A) tail. To perform its
task, poly(A) polymerase has the following characteristic:
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It tightly binds to the downstream poly(A) signal in the RNA
transcript.
Question
9
Which of the following is/are true? You will be penalized for wrong answers.

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a)
The spiceosome proteins are conserved in eukaryotes and
prokaryotes.
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b) The Ran GTPase efficiently hydrolyzes GTP to GDP.
c)
NLS and NES sequences are added post-transcriptionally
to proteins based on their function in the cytoplasm or
nucleus (or both).
x
d) During splicing, snRNAs base pair with pre-mRNA
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Which of the following is not involved in alternative splicing in
eukaryotes?
More than one answer may be correct, so you may select multiple responses. You
will lose partial credit for each incorrect response selected, and gain partial credit
for each correct response selected.
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RNA binding proteins
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the spliceosome
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hnRNPs
x
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self-splicing group II introns