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is 50/50. The predicted outcome is that many fatalities will occur in a short amount of time. 4. In the protonated form, lidocaine does not freely leave cells until it is metabolized.Since lidocaine can freely diffuse into the cell, why does it not diffuse back out when lidocaine levels drop over time in the region of administration (refer to structural differences in Figure 4)Lidocaine is an anesthetic used to reduce pain in the area it is injected into by blocking nerve impulses that send pain sensation to the brain. Since lidocaine can freely diffuse into the cell, the reason that it does not diffuse back out when lidocaine levels drop over time is because it has already been metabolized into thebloodstream. There would be no need for the lidocaine to diffuse back out when
A BOTCHED BOTOX PARTYthe levels drop over time, Lidocaine is giving as an anesthetic it is not used to reverse any effects (Marks, 2014). 5. A-latrotoxin, a neurotoxin in black widow spider venom, also affects acetylcholine (ACh) stimulation of muscle. Interestingly, organisms injected with α-latrotoxin exhibit uncontrollable muscle cramps and spasms, which after some time is then followed by complete flaccid (relaxed) muscle paralysis. Considering what you know about the botulinum neurotoxin, hypothesize how α-latrotoxin may modulate exocytosis of ACh.Acetylcholine is a chemical that functions in the brain and the body and many animals, including humans. Acetylcholine is also a type of neurotransmitter that releases a chemical by nerve cells and sends the information to other parts of the cell. If A-latrotoxin enters the body it will interfere with the acetylcholine and the nerves will not act as a messenger, being the cause of uncontrollable muscle spasms. Botulinum neurotoxins acts by paralyzing somatic motor cells. BoNt usesa process called a clathrin-dependent process. Once BoNt finds its way into the cell in targets proteins by “mediating the exocytosis of the excitatory neurotransmitter,” it will find that acetylcholine is stored here as well. A-latrotoxin may modulate exocytosis of ACh by, binding to ACh receptors on the muscle which will stimulate a contraction. A chemical reaction may form allowing for the stimulation of skeletal muscles. (NCBI, 2017)
A BOTCHED BOTOX PARTYConclusion The scientific concepts that the researchers learned are the effects of acetylcholine, how impaired vision is created by ptosis, and the effects of botulinum neurotoxin in the body. ACh is important for the eyelid to go back to normal after ptosis. Acetylcholine is the most widely spread neurotransmitter in the body. It can be found in the central and peripheral nervous systems, as well as the other body systems. In the cardiovascular system, ACh is used as a vasodilator to lessen cardiac rate. The effect of botulinum is essential to Ach. BoNT (botulinum neurotoxin) inhibits the active transport of ACh by exocytosis. The synapse is the place where these actions occur, and researchers now know that the muscle on the postsynaptic side is dependent on ACh and ACh receptors to stimulate muscle contraction. Botulinum neurotoxin known as Botox is used world-wide and often most people fail to understand the consequences of using this drug. The