B cells now termed antibody producing cells or apcs

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• B Cells (now termed Antibody-Producing Cells or APCs) would produce and secrete Antigen-Specific Antibody Molecules • Antibodies bind to Antigens and tag them for Disposal D. • T H 2 Helper T Cells would provide IL-4, IL-5 and IL-10 that would activate B Cells. • B Cells (now termed Dendritic Cells) would produce and secrete Antigen-Specific Antibody Molecules • Antibodies bind to Antigens and tag them for Disposal 17. Which of the following could initiate the Classical Complement Pathway? A. • A single (1) IgM in its “Planar” Circulatory Configuration - and/or - • Two (2) bound IgA B. • A single (1) IgM in its “Staple” bound Configuration - and/or - • Two (2) bound IgG C. • A single (1) bound IgM - and/or - • Two (2) bound IgA - and/or - • Two (2) bound IgG D. • Two (2) bound IgM - and/or - • Two (2) bound IgA - and/or - • Two (2) bound IgG
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MIC 101 Exam 2 Page 15 18. While in Germany, Shibasaburo Kitasato ( ) did pioneering Work on Clostridium tetani , the Gram Positive, Spore-Forming Bacterium responsible for Tetanus and showed that it was not the Bacterium itself but a Toxin produced by the Bacterium that caused Tetanus. Kitasato and Emil Behring developed a Treatment for Tetanus. This consisted of injecting Antibodies specific for the Toxin. The Binding of these Antibodies to the Toxin in the Bloodstream would effectively prevent the Toxin from attaching to and damaging Cells. Since the Patient ʼ s Immune System is “Passive” in this Treatment it is termed “Passive Immunization”. Behring received large Royalties for Passive Immunization using Tetanus Antitoxin throughout the First World War and was decorated by the German Government for his Work. Kitasato received neither Credit nor Royalties, and he remains virtually unknown outside of his Native Japan. Kitasato became the first Dean of Medicine at Keio University and was the first President of the Japan Medical Association. He was ennobled with the Title Danshaku (Baron) in 1924. Passive Immunization using Tetanus Antitoxin is a Classic Example of -- A. • Neutralization. • The Antitoxin could have been any Antibody Class. B. • Opsonization. • The Antitoxin must have been IgG. C. • Complement Fixation • The Antitoxin must have been IgG or IgM D. • Antibody-Dependent Cell-mediated Cytotoxicity (ADCC) • The Antitoxin must have been either IgG, IgA or IgE Check your ScanTron. You have just answered Question 18. Proceed to Question 19. Natural Killer Cells are like Ninja. Cytotoxic T Cells are like Samurai. - Nori San
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MIC 101 Exam 2 Page 16 19. Shortly after the Battle of Britain, Peter Medawar was sent to the Burns Unit of the Glasgow Royal Infirmary (where Lister did his pioneering Work on Antiseptic Surgery). He became Friends with the Physician Tom Gibson, and together they undertook an Investigation of Skin Graft Rejection. Medawar and Gibson proposed that Skin Graft Rejection was mediated by the Immune System.
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