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If a female has a defective gene on one of her two x

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If a female has a defective gene on  one of her two X chromosomes, she  will be protected from its effects by  the normal gene on her second X  chromosome Chromosome     mutations
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ESCI 274 Genetics, the Environment and Health Chromosome     mutations
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ESCI 274 Genetics, the Environment and Health Chromosome     mutations
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ESCI 274 Genetics, the Environment and Health Chromosome     mutations
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ESCI 274 Genetics, the Environment and Health Chromosome     mutations
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ESCI 274 Genetics, the Environment and Health Sequence variation Environmental exposure Chromosome +  DNA  +  Gene  + Protein
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ESCI 274 Genetics, the Environment and Health DNA  +  Gene    sequence variation
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ESCI 274 Genetics, the Environment and Health Abnormal or non-functioning protein Environmental exposure Chromosome + DNA + Gene +  Protein
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ESCI 274 Genetics, the Environment and Health Protein (mutation effects on gene expression) Hypo morphic mutations  Mutations that cause  reduced function  of  the gene product, or a negative change  in the expression of the gene
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ESCI 274 Genetics, the Environment and Health Protein (mutation effects on gene expression) Hyper morphic mutations  The opposite of  hypo morphic mutations;  they cause  increased activity  or  expression of the gene product
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ESCI 274 Genetics, the Environment and Health Protein (mutation effects on gene expression) Neo morphic mutations  Cause a  novel or new protein molecular  function  or  expression of the gene product
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ESCI 274 Genetics, the Environment and Health Protein (mutation effects on gene expression)
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ESCI 274 Genetics, the Environment and Health Health or Disease? Changes in DNA caused by mutation  can cause  errors in protein sequence,  creating   partially or completely  non-functional proteins To function correctly, each cell depends on  thousands of proteins to function in the  right places at the right times
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ESCI 274 Genetics, the Environment and Health Health or Disease? When a mutation alters a protein that  plays a critical role in the body a medical condition can result A condition caused by mutations in one or  more genes is called a  genetic disorder   However,  only a small percentage of  mutations cause genetic disorders most have no impact on health
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ESCI 274 Genetics, the Environment and Health Health or Disease? Often, gene mutations that could cause  a genetic disorder are repaired by the  DNA repair system  of the cell
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ESCI 274 Genetics, the Environment and Health Health or Disease?
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