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Unformatted text preview: H. Linkage of Course Objectives and Curricular Outcomes Immunology (PHRM 525) – Syllabus Page 1 of 6 o The knowledge, understanding and application of the biomedical sciences (Obj # 1-6) o The ability to think critically and problem solve (Obj #3-7) o Effective communication through written and verbal means (Obj #6-7) o The highest level of professional, legal, and ethical behavior (Obj #1-7) I. Topical Course Outline Students are expected to read the textbook chapters before class to gain an initial understanding of the material and to identify confusing points that they can ask to be clarified in class. A lecture outline and a list of learning objectives for each lecture will be provided on Pulse for each scheduled lecture. Class # Date Day Time Topic Faculty Resource 1 29-Aug Wed 10:00 Course Overview, General Introduction Calkins 2 30-Aug Thurs 11:00 Elements of the Immune System and their Roles in Defens e; Antigens, recognition and activation; Cells, Tissues, Migration Calkins 3 5-Sep Wed 10:00 Immunology in Pharmacy Careers Chaballa Schafer Shay 4 6-Sep Thurs 11:00 Principles of Adaptive Immunity; Steps from recognition to protection and memory; Clonal Selection; T- and B-Cell Responses; advantages/disadvantages Calkins 5 10-Sep Mon 11:00 Innate Immunity; Mechanisms of immune defense, Complement system, PAMPS, TLRs, induction of inflammation Alugupalli 6 12-Sep Wed 10:00 Innate Immunity (continued); Mechanisms of protection: Induction/activation of leukocytes, phagocytosis/killing, granuloma, Cytokines/chemokines/ anti-virals Alugupalli 7 13-Sep Thurs 11:00 Team-Based Learning: Adaptive vs Innate Immunity Quiz Students 8 17-Sep Mon 11:00 Antibody Structure and Function; General structure, isotypes, antigen-binding, effector functions; monoclonal antibodies; practical applications Sukulev 9 19-Sep Wed 10:00 Generation of Antibody and T Cell Antigen Receptor Genes ; Repertoire diversity, regulation of antigen receptor gene expression Manser 10 20-Sep Thurs 11:00 Antibodies as Drugs/Therapeutics ; Multiple effector functions; Antibodies as drug carriers; efficacy vs safety Magee Exam #1 24-Sep Mon 11:00 Exam #1; 50 min. NA 11 26-Sep Wed 10:00 Immune-Based Diagnostics; Detection of antibodies/antigens; characterization of cells, phenotypically and functionally; assessment of immune responses and immune competence Calkins 12 27-Sep Thurs 11:00 Team-Based Learning: Immunodiagnosis Quiz Students 13 1-Oct Mon 11:00 Antigen Recognition by T Lymphocytes; Antigen processing, Major Histocompatibility Complex (MHC), peptide binding groove and anchor residues, Human leukocyte Antigen (HLA) Hersperger Immunology (PHRM 525) – Syllabus Page 2 of 6 14...
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- Fall '12
- The Land, ........., Week-day names, Catherine Calkins