oncogene, or cancer-promoting gene, called LMO-2, which can spur childhood leukemia because the virus lands randomlyInvolves using viruses to introduce healthy genes into cellsGene Therapy has caused chickenpox and can significantly increase the production of white blood cells, result in an enlarged spleen, anemia and a decrease in platelets For gene therapy Partner Notes:Gene therapy is an effective treatment for HIV and the fight against AIDS by reducing viral loads, preserving the immune system and avoiding lifelong antiviraltherapyHas cured “bubble boy” disease by using the vector rotavirus to add a normal copy of the faulty gene to the stem cells by altering the spikes on its surface to transfer the gene more effectively because this disease causes the disease on the X chromosome and stops the development of T cellsHas occurred deafness in Guinee pigs which promotes the regrowth of of crucial hair cells in the cochleaHas been proven that it could one day help muscular dystrophy in which the gened can get into muscle cells all over the body to avoid muscle cells from breaking down and being replaced by fatCan improve sight in people with a rare form of blindness in which vision was restored in 4/6 people. This is achieved by replacing the faulty gene with a normal version of the protein in the retina which senses light and sends messages to the brainConsensus:We are for gene Therapy!Group paragraphs:We have come to a consensus that gene therapy should be continued. Although there are some very severe alternatives such as death or cancer, the positives of gene therapy outweigh its cons. Gene Therapy has helped so many people who have had lifethreatening diseases, and it has also improved the quality of life, in several cases. Mostof the time, eliminating the faulty gene, and increasing the expected life span has been successful by use of viral and non-viral vectors.However, I do think that more research is necessary before performing a gene therapy study. Being more familiar with the risks of the study can eliminate the chances of deathand unnecessary diseases. By being more educated about the effectiveness the vector will have on a specific faulty gene, we can find additional ways on how to avoid the replacement of DNA triggering the wrong gene. This is important because in most casesthe cause of something going wrong has been linked to the DNA attaching to the wrong gene, as it does randomly.© 2010 Project Lead The Way, Inc.Medical InterventionsActivity 2.2.1 Student Response Sheet – Page 5
Response Sheet modified from Genetic Science Learning Center – Gene Therapy: Molecular Bandage?Article about gene therapy being used for a disease, disorder or condition NOT discussed in this activity:Key points of the article:The article I found is located on this site below: Arthritis is an autoimmune disease with inflammation of and synovial hyperplasia that results in degradation of cartilage and bone Gene therapy aids in the efficient and sustained delivery of inhibitors of
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- Fall '16
- Erin morse