Interpreting dose effect curves dose response curves

Info icon This preview shows pages 16–23. Sign up to view the full content.

View Full Document Right Arrow Icon
Interpreting dose-effect curves Dose-response curves can also provide a measure of potency ; the dose needed to produce a particular effect of a given intensity Potency also varies inversely with the magnitude of dose depends on inherent ability of the drug to bind to a receptor (affinity=Kd) Depends on factors regulating how much drug reaches the site of action Comparative expression of drug activity at a particular site ( relative to a standard of reference )
Image of page 16

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 17
Image of page 18

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon