Video 6 Calcium build-up in the arteries can cause heart-attacks in postmenopausal women o A recent study of ~1,500 women with a mean age of 74 taking calcium supplements had a ~50% chance of having either a heart attack or stroke compared with those taking a placebo o What to do?
It has been determined that calcium uptake is better when vitamin D is enhanced (another therapy for osteoporosis) Vitamin D has been shown to increase calcium uptake when the two supplements are taken together Exercise – stimulates bone density and bone mass increase Adolf Windaus worked out Vitamin D’s relationship with calcium o Vitamin D maintains calcium; need UV-B; about 500 IU/day Video 7 Estrogen therapy o Estrogen receptors are found in bone cells o Post-menopause – decrease in estrogen levels o Estrogen helps prevent osteoporosis and may help prevent heart disease, but increases the risk of uterine cancer and may increase the risk of breast cancer One study found that Prempro (estrogen and progestin combined) increased the risk of breast cancer, heart attack, and stroke, BUT even more so did Premarin (estrogen only) Prempro reduces the risk of uterine cancer One study found that the risks (heart attacks, stroked, breast cancer, blood clots) of long-term estrogen plus progestin therapy outweigh its protective benefits (colorectal cancer, hip fractures) Osteoporosis summary: o Adequate calcium intake early in life reduces risk Calcium supplements can be part of this intake o Estrogen supplements after menopause reduce the risk o Calcium supplements can reduce dose of estrogen required o Estrogen is associated with uterine cancer and may cause breast cancer, but the overall risk of it is relatively low
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- Spring '11
- Sodium, Sodium chloride, Ca