Drug to Drug Interactions penicillin G oral contraceptives Digoxin Copyright

Drug to drug interactions penicillin g oral

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Drug-to-Drug Interactions – - penicillin G, oral contraceptives, Digoxin
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Nursing Considerations for Patients Receiving Tetracyclines Nursing Considerations for Patients Receiving Tetracyclines Assess: Known allergy to any tetracycline or to tartrazine Physical examination Skin for any rash or lesions Culture and sensitivity tests Respiratory status Renal and liver function test reports
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Prototype Summary: Tetracycline Prototype Summary: Tetracycline
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Question Question Tell whether the following statement is true or false. Sulfonamides should not be given with thiazide diuretics because of a cross sensitivity of the drugs.
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Answer Answer True Rationale: Drug-to-Drug Interactions: Cross sensitivity with thiazide diuretics; Sulfonareas
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Antimycobacterial Antimycobacterial Contain pathogens causing TB and leprosy Most common medications- Rifabutin ( Mycobutin ), isoniazid (generic), rifampin ( Rifadin ), pyrazinamide (generic), ethambutol, ( Myambutol ), streptomycin (generic), and rifapentine, ( Priftin )
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Antimycobacterial Cont. Antimycobacterial Cont. Action- Act on the DNA of the bacteria leading to lack of growth and eventual bacterial death for TB and Leprosy Indications- Treatment of TB and Leprosy Pharmacokinetics- Well absorbed from the GI tract Metabolized in the liver, excreted in the urine, cross the placenta and enter breast
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Antimycobacterial Cont. Antimycobacterial Cont. Contraindications Allergy, renal or hepatic failure, CNS dysfunction and pregnancy Adverse Effects CNS effects and GI irritation Drug-to-Drug Interactions Rifampin and INH can cause liver toxicity
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Nursing Considerations for Patients Receiving Antimycobacterials Nursing Considerations for Patients Receiving Antimycobacterials Assess: Known allergy to any antimycobacterial drug History of renal or hepatic disease and CNS dysfunction Physical examination Skin for any rash or lesions Culture and sensitivity testing Respiratory status and evaluate renal and hepatic function tests
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Prototype Summary: Isoniazid Prototype Summary: Isoniazid
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Other Antibiotics Other Antibiotics Ketolides, Lincosamides, Lipoglycopeptides, Macrolides, Oxazolidinones, Monobactam , Antibiotics that do not fit into the large antibiotic classes Most common medications- telithromycin ( Ketek ), telithromycin, Clindamycin (Cleocin) televancin ( Vibativ ), dalbavancin ( Dalvance ), and oritavancin ( Orbactiv ), azithromycin (
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