# 2 points which patient has a larger pulse pressure

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(2 points) Which patient has a larger pulse pressure? Compare these results to apatient with normal blood pressure (PS= 120 mm Hg, PD=80 mm Hg).B.(5 points) Which patient has a more stressed heart? This can be determined bycalculating the stroke work (SW) required to pump the blood out to the body. Assumethat both patients have exactly the same end diastolic and end systolic volumes in theleft ventricle at 160 and 80 ml, respectively. Also assume that the heart can be modeledas a perfect, frictionless piston with no heat generation. Recall that this simplificationallows SW to be expressed as follows:Again compare these results to a patient with normal blood pressure.C.(6 points) Which patient is more likely to be suffering from arteriosclerosis? This can bedetermined by calculating the peripheral resistance (p). Assume that both patientshave a heart rate of 65 beats/min. Again compare to a normal patient.D.(2 points) Based on your results, explain why it is important to know your systolic anddiastolic blood pressures separately, and not just your pulse pressure?SW=PdVName: _______________________________________5
4. Cardiovascular mechanics and system integration (20 points)You are given the following information about a patient:Ca= 2.5 mL/mm HgVoa= 0.5 LVT= 5 LCv= 120 mL/mm HgVov= 2 LQ = CO = 5 L/minA.(4 points) Write out the four equations that relate blood flow, pressure, and volumes inthe systemic circulation (arteries, microcirculation, and veins).B.(4 points) If the patient’s total peripheral resistance (p) is 0.02 min·mm Hg/mL,calculate the resulting venous pressure (PV).C.(6 points) On hot days, the body can cool itself by increasing flow through themicrocirculation closer to the surface of the skin. This can be effectively modeled by adecrease inp. Forp= 0.01 min·mm Hg/mL, calculate the new arterial and venousconditions. Would you anticipate a change in heart function? If so describe all of thesechanges and their effects.D.(6 points) Now imagine the patient is back inside and their system has returned to theconditions in part B. But another way your body worked to cool you down was to sweat,so now you are very thirsty and rapidly drink an entire liter of water. Assuming that theactual amount of water lost from sweat was negligible, and that the water you drankinstantaneously passed from the stomach into the arterial circulation, determine the newarterial and venous conditions if Q andpare constant. How do you think the body willchange due to systemic regulation?

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