Not especially tumor specific damage to normal tissue

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Not Especially Tumor-specific; Damage to Normal Tissue Can Limit Utility Limited Utility Against Extensive, Systemic Disease (Unless tumor cells can be specifically targeted, e.g. with Tumor- specific antibody delivering bound-metal for microwave heating) Can be Valuable for Debulking Large Local Tumor or Reducing Tumor Size to Permit Surgery Second Malignancies Can Be Induced Combination with Radio-sensitizers Can Improve Anti-tumor Specificity Limited by Tumor Heterogeneity and Selection for Radiation-resistant Variants Radiate
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Therapies Involving Electromagnetic Radiation: Part 2: Photodynamic Therapy, Hyperthermia, Neutron Capture, Microwave or Radiowave Therapy External physical intervention with a physical target: (the cancer cell or cancer mass) Must know where the cancer mass is Must be able to direct the physical intervention e.g. Laser-directed microwave Utility against cancers not accessible to surgery Damage to normal tissue must be circumvented Emergence of resistance is unlikely Radiate
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Possibilities with Ultra-sonic Radiation External physical intervention with a physical target: the size and sonic sensitivity of the cell. Emergence of cellular resistance based on cancer cell biochemistry is not possible. Target is a necessary physical state ( enlarged cell size at mitosis ) through which the dividing cancer cell must pass, no matter how it got to that state.
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  • Spring '11
  • ThomasFondy
  • Oncology, Chemotherapy, External physical intervention

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