First identified because they stimulated the

Info icon This preview shows page 32. Sign up to view the full content.

first identified because they stimulated the proliferation of fibroblasts; now known to regulate neuronal and glial proliferation and be the major mitogenic species in nervous system; 4 genes/receptors for FGFs but multiple splice variants so a large variety of targets; distinct subfamily of RTKs Transforming growth factor : larger superfamily with 24 members arranged into subfamilies; GDNF signals through a dimerized RTK Epidermal Growth Factors : EGF (stem cells) Neuregulins (arise from alternative splicing of a single gene); ~12 isoforms; secreted proteins with a region homologous with EGF; bind to a family of RTKs called erbBs
Image of page 32
This is the end of the preview. Sign up to access the rest of the document.
  • Spring '13
  • Szumlinski
  • Morphine, opioid peptides

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern