Lecture8_Nucleosome v2

Dna dna interaction osmotic stress dna dna

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DNA-DNA Interaction: Osmotic Stress DNA-DNA Interaction: Osmotic Stress Measurements Measurements d where F 0 =55000pN/nm 2 and c=.27nm. The measured pressure can be turned into an interaction energy between pairs of DNA strands. This energy, per strand length is: Rau and Parsegian
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(nm) λ T7 (nm) Percent packed asymptote Comparison With Experiments: Comparison With Experiments: Geometry of Packing Geometry of Packing Spacing of packaged DNA in capsids has been measured by cryoEM and x-rays. (Cerritelli et al .)
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HK97 Wikoff Percent packed Force (pN) T7 HK97 λ φ 29 T4 Consider several other bacteriophage under same conditions as that of the Bustamante experiment. Maximum force in the case of T7 nearly a factor of two larger than that in phi29. (Significance for motors in these other phage?) Predictions for Packing Forces in Other Predictions for Packing Forces in Other Phage Phage (Jardine et al .)
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How Big is a Genome? Part 2 How Big is a Genome? Part 2
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Polymers as Random Walks Polymers as Random Walks Bustamante et al.
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