Arv side effects and drug food interactions may lead

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ARV side effects and drug-food interactions may lead to poor adherence to drug regimens especially during the early stages of HAART, so supporting clients to manage side effects and interactions can help ensure good adherence. NUTRITION-RELATED SIDE EFFECTS OF ARVs While ARVs contribute to improved nutritional status, in some cases they cause dietary and nutritional constraints that require nutritional interventions including high blood cholesterol, high triglycerides, peripheral neuropathy, liver damage and kidney stones. Some of the nutrition- related side effects of common ARVs used in Kenya include loss of appetite, nausea/vomiting, diarrhea, anemia, constipation, changes in body composition, etc. However, careful selection of food, well planned meals and a drug schedule can minimize the side effects and improve adherence to and effectiveness of ARVs. BODY COMPOSITION SIDE EFFECTS OF ARVs The common and predominant signs of fat redistribution syndromes [lipodystrophy] include facial and limb fat wasting, central and/or localized adiposity and increased fat around the abdomen. Sometimes the manifestations include lipoatrophy syndrome, marked by predominant loss of subcutaneous fat from limbs, buttocks and face, which can lead to loss in total body weight, a side effect of HAART. FOOD AND NON-ART DRUG INTERACTIONS Other medications used by PLWHA can negatively affect food and nutritional outcomes like causing bitter and unpleasant after-taste. PLWHA should avoid taking medications that have not
been prescribed by their clinician or service provider. Also, foods rich in certain chemicals may cause severe side effects when taken together with certain drugs. HERBAL REMEDIES Besides treatment, herbs and spices are used to enhance food’s taste and smell and improve appetite. However, though they are beneficial, they may interfere with some of the effects of drugs and have negative effects on the body, or restrict food intake. Herbs can e used by PLWHA as long as; They are used as supplements and not replacement for standard therapy They are not toxic and do not overburden the body’s ability to metabolize and eliminate them They have no significant negative interactions with medications They have the potential to prevent, alleviate and/or cure symptoms DIETARY SUPPLEMENTS They are available as single or multiple micronutrients alone or with herbal formulations or supplements containing micronutrients and selected amino acids alone or with herbs. Selected probiotics and prebiotics or their combination [synbiotics] may also play a significant role in nutritional care of PLWHA.
CHAPTER 8 FOOD SECURITY FOR HOUSEHOLDS AFFECTED BY HIV/AIDS HIV/AIDS can reduce the food security of PLWHA and affected households limiting the capacity for nutritional care and support. Household food security requires that a household has access to enough quality and culturally acceptable food for all people in the home throughout the year and its components are availability, accessibility and utilization.

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