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27 a 20 year old man with phimosis should be

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27.A 20-year-old man with phimosis should be instructed to apply betamethasone (Sernivo) 0.05%cream at least twice daily for:
3 days.7 days.3 weeks.6 weeks.CorrectExplanation:Topical steroid creams can help soften tightened foreskin and facilitate retraction.Steroids should be applied to the tight rink of foreskin and head of penis twice daily for6-8 weeks.28.A 45-year-old man is receiving finasteride (Proscar) for the symptomatic treatment of benignprostatic hyperplasia. The patient should be advised that:prostate specific antigen (PSA) levels may increase.it should be crushed and taken with food.his medication should not be handled by a pregnant or lactating relative.Correcthe will see benefits of therapy within 2-3 months of initiation.Explanation:Finasteride (Proscar) is unsafe if handled by women who are pregnant or lactating.Women should not handle crushed or broken Proscar tablets when they are pregnant ormay potentially be pregnant due to risk to a male fetus. The mechanism of action of thismedication is to convert testosterone to the androgen dihydrotestosterone.29.Ciprofloxacin, used for the treatment of bacterial prostatitis, is a potent CYP1A2 inhibitor and isabsolutely contraindicated with other CYP1A2 inhibitors. An example of another CYP1A2inhibitor is:ketoconazole.tizanidine (Zanaflex).Correctfluoxetine hydrochloride (Sarafem).celecoxib (Celebrex).Explanation:Ciprofloxacin, a fluoroquinolone, is a strong CYP1A2 inhibitor and is absolutelycontraindicated for concomitant administration of tizanidine (Zanaflex). Concomitantuse may increase the serum concentration of tizanidine. If use with another stronginhibitor cannot be avoided, initiate tizanidine at an adult dose of 2 mg and increase in2-4 mg increments based on response. Ketoconazole is a CYP3A4 inhibitor; celecoxib isa CYP2D6 inhibitor; and fluoxetine is a YP2C19 inhibitor. CYP1A2 inhibitors are enzymes
that catalyze many reactions involved in drug metabolism and synthesis of cholesterol,steroids and other lipids.30.Fluoroquinolones used to treat prostatitis are NOT effective against:Proteus mirabilis.Pseudomonas aeruginosa.Escherichia coli.Enterococcus faecalis.CorrectExplanation:Fluoroquinolones have demonstrated high bactericidal activity against Escherichia coli,Proteus mirabilis, and Pseudomonas aeruginosa. Fluoroquinolones are generallyineffective against the streptococci, enterococci, and anaerobic species in the prostategland.31.Suppressive antibiotic therapy for chronic bacterial prostatitis is:ciprofloxacin (Cipro) 500 mg daily for 14 days.cephalexin (Keflex) 500 mg twice daily for 30 days.trimethoprim-sulfamethoxazole (Bactrim DS) twice daily for 21 days.trimethoprim-sulfamethoxazole (Bactrim DS) daily, chronically or until urine culture isclear.

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