Fungal infections are most often found on the skin and topical azoles are

Fungal infections are most often found on the skin

This preview shows page 3 - 4 out of 6 pages.

Fungal infections are most often found on the skin and “topical azoles are fungicides that are effective against tinea corporis, tinea cruris, and tinea pedis as well as cutaneous candidiasis” (Arcangelo & Peterson, p. 142). Metronidazole is commonly used to treat trichomoniasis and is only effective against these parasites in the oral form (Arcangelo & Peterson). “Anthelmintics are agents used to eradicate intestinal worms (helminths) from the body ” and are typically oral, but may be used topically depending on the type of infection (Drugs.com, n.d.). Beta-Lactam Antibiotics are useful in treating polymicrobial infections (Arcangelo & Peterson, 2013). Penicillin is a beta-lactam that has been widely used for several years, but due to resistance it is primarily recommended when a pathogen demonstrates sensitivity to it on a culture. Cephalosporins are a beta-lactam group that is divided into four “generations”. First generation cephalosporins, such as Cefazolin, are more efficient against gram-positive bacteria and less potent against gram-negative bacteria. Cefepime, a fourth-generation cephalosporin, demonstrates an increase in gram-negative activity with less gram-positive coverage (Arcangelo & Peterson). Fluoroquinolones, macrolides, sulfonamides, and tetracyclines are broad-spectrum antibiotics that can be used to treat gram-negative, gram-positive, and some atypical organisms (Arcangelo & Peterson, 2013). Aminoglycosides are primarily used to treat gram-negative infections and must be used cautiously due to the risk of nephrotoxicity and ototoxicity associated with these medications (Arcangelo & Peterson). Vancomycin is a glycopeptide with a “narrow spectrum of activity directed toward gram-positive organisms” (Arcangelo & Peterson, p. 110). Arcangelo and Peterson report that it is the drug of choice for MRSA and other resistant
Image of page 3
Image of page 4

You've reached the end of your free preview.

Want to read all 6 pages?

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture