Response Feedback: Acetylcholine and cevimeline are both cholinergic agonists, and, like carbachol, would be contraindicated in this patient. Administration of either of these drugs could be fatal. Nicotine is a direct-acting nicotinic agonist and is not indicated in cholinergic poisoning. Atropine is considered the antidote for cholinergic poisoning. The actions of atropine are a reduction in salivary, bronchial, and sweat gland secretions; mydriasis; cycloplegia; changes in heart rate; contraction of the bladder detrusor muscle and of the gastrointestinal smooth muscle; decreased gastric secretion; and decreased gastrointestinal motility. Question 14 1 out of 1 points A patient who is experiencing acute alcohol withdrawal is being treated with intravenous lorazepam (Ativan). This drug achieves a therapeutic effect by Response Feedback: Like all benzodiazepines, lorazepam increases the effects of GABA, which has an inhibitory effect on the CNS. However, none of the benzodiazepines act like GABA or
increase the amount of GABA present. MAOIs inhibit monoamine oxidase and tricyclic antidepressants primarily affect serotonin and norepinephrine levels. SSRIs increase the availability of serotonin in the synapses. Question 15 1 out of 1 points A patient has been admitted to the ICU because of multiple traumas due to a motor vehicle accident. The physician has ordered propofol (Diprivan) to be used for maintenance of sedation. Before administration of propofol, a priority assessment by the nurse would be to check for a history of Response Feedback: Propofol is relatively contraindicated in patients with a history of seizure disorders because they are at risk of developing convulsions during the recovery phase. This drug should be used with caution in patients with low blood pressure because it can aggravate this condition. Also, it should be used with caution in patients with increased intraocular pressure because it can cause a substantial reduction in cerebral perfusion. Because disorders of lipid metabolism can be aggravated by the emulsion vehicle in which propofol is delivered, it should be used with caution in patients with diabetic hyperlipidemia. Question 16 1 out of 1 points A nurse will be prepared to administer naloxone (Narcan) to a patient who has had an overdose of morphine. Repeated doses of Narcan will be necessary because Narcan Response Feedback: The duration of the morphine may be longer than the duration of naloxone. Therefore, naloxone has a shorter half-life than morphine. Repeated doses may be necessary to maintain reversal of the opiate's effects. Naloxone does not increase the action of morphine, and it causes the respiratory rate to increase, not decrease. Dosage strength is not associated with drug duration.
- Summer '15
- Pharmacology, Morphine, Benzodiazepine, Benzodiazepine withdrawal syndrome