Storage and release 1 neuropeptides are synthesized

Info icon This preview shows pages 10–16. Sign up to view the full content.

View Full Document Right Arrow Icon
Storage and release 1: Neuropeptides are synthesized by transcription, translation and posttranslational modifications in the cell body and axon (similar to any other protein) 2: Stored in large, dense core vesicles that are assembled in the Golgi network 3: Dense core vesicles are transported down the axon on microtubules 4: Dense core vesicles are docked outside of the active zone and are released upon large and sustained calcium entry into the cell (rapid train of action potentials) 1 2 3 4
Image of page 10

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon