o Matrix Ground Substance Protein fibers Collagen Elastin Non Cellular Matrix

O matrix ground substance protein fibers collagen

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o Matrix = Ground Substance + Protein fibers (Collagen, Elastin) - Non-Cellular Matrix of blood o Plasma, composed of an aqueous mixture of proteins - A distinguishing feature is that all produce a non-cellular matrix such as, hard bone and cartilage. - All produce non-cellular matrix providing support, cushion, transport - Types: o Loose Between skin and organs o Dense Tendons, ligaments, sheathing around muscles o Special Cartilage, bone, and blood Muscle Tissue - Specialized for contraction - Three Types o Smooth (Involuntary/ autonomic) Blood vessels Digestive tract o Skeletal (Voluntary/somatic) Attach to bones o Cardiac Heart only Involuntary Nervous Tissue - Neurons are specialized to conduct impulses - Neuroglia support neurons - Conduct electrochemical signals called impulses The Integumentary System - Epidermis: Composed primarily of stratified squamous tissue - Dermis - Subcutaneous layer: Primarily adipose tissue and anchors the skin o Technically not part of the integumentary system - Accessory organs Skin Functions - Protection o Water loss Keratin o Pathogens o UV Radiation
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Melanocytes Malignancy starts with damage to normal cell genetics (p53 gene mutation) DNA absorbs UV light and can mutate o Physical Damage - Regulates body temperature - Synthesis of Vitamin D - Senses the external environment Homeostasis - Important homeostatic conditions o Temperature o pH o Glucose concentration o Oxygen concentration - Negative Feedback o
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