capable of prolonging the QT interval are capable of causing ventricular tachyarrhythmias . Pyridostigmine (used for myasthenia gravis) pt starts increased salivation, urination and lacrimation – what should RN do?- inform HCP. This is cholinergic crisis. These are signs and symptoms of cholinergic crisis. The client can get increasingly worse. The primary healthcare provider can prescribe atropine as treatment of overdose. Pyridostigmine (Mestinon) is an oral cholinesterase inhibitor. Acetylcholine is one of many neurotransmitters in our bodies. Neurotransmitters are chemicals that help
our cells communicate with each other. Depending on the organ that it acts upon, acetylcholine produces different effects. One important function of acetylcholine is to produce muscle contractions and movement. In people with myasthenia gravis or people treated with neuromuscular blocking medicines there is a decrease in the levels of acetylcholine. In such cases pyridostigmine may be used to increase acetylcholine levels and improve muscle contraction or movement. Pyridostigmine increases the concentration of acetylcholine at nerve junctions by inhibiting cholinesterase, the enzyme that destroys acetylcholine . MMR is given SQ. Subcutaneous injections are administered in the fat layer, underneath the skin. When administering SQ injections use a 23-25 gauge needle, needle length for infants (1- 12 months) is 5/8”, children 12 months and older 5/8” – ¾”. Metronidazole is an antibiotic used for the treatment of vaginal infections. Metronidazole and alcohol can interact with each other, causing severe nausea and vomiting as well as cramping and flushed appearance. Both cyclosporine and azathioprine are immunosuppressants. Clients should be taught to protect themselves from sources of infection. Vaccinations are not given to immunocompromised clients. Avoidance of crowds will decrease the client's chance of contact with infections, especially those spread by droplets. As a general rule, significantly immunosuppressed clients should not receive live vaccines. Cyclosporine may cause growth of extra tissue in your gums so use a dentist regularly. These drugs are teratogenic. Clients should avoid pregnancy while on these medications by use of contraceptives. Levofloxacin is contraindicated in clients with a history of myasthenia gravis because it may cause the condition to become worse. Myasthenia gravis results in a breakdown in the communication between muscles and nerves and is characterized by muscle weakness. The most commonly affected muscles are those of the eye, face, throat, neck and limbs. Low doses of dopamine (0.5-5 mcg/kg/min) cause vasodilation and increased diuresis. High doses (5-10 mcg/kg/min) cause vasoconstriction to increase blood pressure and improve cardiac output.
- Winter '16
- Non-steroidal anti-inflammatory drug