Meningitis and severe pneumonia in children under 5

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meningitis and severe pneumonia in children under 5 End 2012: Hib vaccine had become part of national immunization schedules in 173 countries and introduced in 184 countries Global coverage with 3 doses of Hib vaccine was estimated at 45% in 2012 91% in the Americas Only 11% in South-East Asia 1 st vaccine to prevent a major cause of cancer!
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Pentavalent Vaccine A single vaccine delivered in 3 doses that protects against diphtheria, pertussis, tetanus, HepB, and Hib Saves money and ensures broader coverage by minimizing the number of visits needed Global coverage of the pentavalent vaccine is expected to increase from 50% in 2011 to more than 90% in 2020
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Pneumococcal Conjugate Vaccine Pneumococcus is the bacterium that causes pneumonia Pneumococcal vaccine coverage is projected to rise from approximately 6% in 2011 to approximately 89% by 2020 across 94 low- and middle-income countries Average dose 2015 = $3.30 and $7.00
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Rotavirus Vaccine Most common cause of severe diarrheal disease among children under 5 Although 2 vaccines are available, they are not yet widely used in low-income countries WHO recommends that all infants be vaccinated Rotavirus vaccine coverage is projected to rise from 2% in 2011 to 77% by 2020 across 94 low- and low-middle income countries
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Yellow Fever Vaccine An acute viral hemorrhagic disease transmitted by mosquitoes WHO currently recommends vaccinating all infants over 9 months living in endemic areas Average dose 2015 = $0.77–$1.17
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Human Papillomavirus (HPV) Vaccine 70% of cervical cancer caused by HPV The vaccine is given to children aged 9 to 13 (prior to initiation of sexual activity) The vaccine has been introduced in more than 45 countries Average dose 2015 = $4.55 Men starting to get vaccinated?
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MenAfriVac The Meningitis Vaccine Project (MVP), a partnership between PATH and WHO, developed a vaccine against meningococcal A meningitis for use in sub-Saharan Africa Expected to reduce endemic meningitis by 50% Costs under $0.50 per dose Introduced in December 2010 and more than 150 million people have received the vaccine
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Next Generation of Vaccines and Vaccine Delivery WHO anticipates = cholera, dengue, malaria, polio, and typhoid will be introduced during the “Decade of Vaccines” Began in 2010 Research is under way to develop new vaccine formulations that are safer, easier to store and transport due to thermostability, and packaged in smaller vials to decrease waste
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Progress Toward Universal Immunization of Children Today: vaccine-preventable diseases remain a major cause of morbidity and mortality around the world 2012: 1.5 million children died from vaccine- preventable disease 2013: 21.8 million infants were not vaccinated at all
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Progress Toward Universal Immunization of Children Vaccination is consistent w/“inverse care law”: Observes that the availability of good medical care tends to vary inversely with the need of the population.
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  • Fall '08
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Christopher Reinemann
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