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j.Differentiate between the structure, pathogenic properties and mechanisms by which bacteria, viruses and fungi cause disease.
more resistant than gram positive bacteria to antibioticswall they contain endotoxins, which are released when the bacteria islysed. Endotoxins cause fever, hypotension, DIC and septic shock and are not neutralize by antibioticsGRAM POSITIVE BACTERIAStaph aureus Strep pyogenesStrep. Pneumoniaee.colic. perfringesc diffshigellastaphstrepbacillus (anthrax)clostridium (tetnus)Some gram-positive bacteria secrete teichoic acid which helps to protect them from complement mediated lysise they retain the purple gramstain. They lack the extra cell membrane and release exotoxins. There are three types of exotoxins, Type I, Type II and Type III. Type I exotoxins interact with MCH Class II proteins and stimulate the over production and release of proinflammatory cytokines. Type I exotoxins are responsible for food poisoning from staph aureus,toxic shock syndrome from staph aureus, and scarlet fever from strep pyogenes. Type II exotoxins cause damage to cell membranes. Type II toxins may be found in Strep. Pneumoniae, some E coli, and C. perfringes