When prescribing medroxyprogesterone (Depo Provera) injections, essential education would include advising of the following potential adverse drug effects: 1 . Hypertension & dysuria 2 . Depression & weight gain 3 . Abdominal pain & constipation 4 . Orthostatic hypotension & dermatitis 15. The medroxyprogesterone (Depo Provera) injection has a Black Box Warning due to: 1 . The potential development of significant hypertension 2 . Increased risk of strokes 3 . Decreased bone density 4 . The risk of a life-threatening rash such as Stevens-Johnson 16. Shana received her first medroxyprogesterone (Depo Provera) injection 6 weeks ago & calls the clinic with a concern that she has been having a light “period” off & on since receiving her Depo shot. What would be the management of Shana? 1 . Reassurance that some spotting is normal the first few months of Depo & it should improve. 2 . Schedule an appointment for an exam as this is not normal. 3 . Prescribe 4 weeks of estrogen to treat the abnormal vaginal bleeding. 4 . Order a pregnancy test & suggest she use a back-up method of contraception until she has her next shot. 17. William is a 62-year-old male who is requesting a prescription for sildenafil (Viagra). He should be screened for before prescribing sildenafil. 1 . Renal dysfunction 2 . Unstable coronary artery disease 3 . Benign prostatic hypertrophy 4 . History of priapism 18. Men who are prescribed sildenafil (Viagra) need ongoing monitoring for: 1 . Development of chest pain or dizziness 2 . Weight gain 3 . Priapism 4 . Renal function 19. Men who are prescribed an erectile dysfunction drug such as sildenafil (Viagra) should be warned about the risk for: 1. Impotence when combined with antihypertensives 2. Fatal hypotension if combined with nitrates 3. Weight gain if combined with antidepressants 4. All of the above 20. &rogens are indicated for: 1. Symptomatic treatment for male deficiency 2. Female libido, endometriosis, & postmenopausal symptoms ADV Pharm | TextBook | StudyGuide 56
3. Increased muscle mass 4. Symptomatic treatment in both sexes for cancer & HIV 5. 1, 2, & 4 6. All of the above 21. Long-term use of &rogens requires specific laboratory monitoring of: 1 . Glucose, calcium, testosterone, & thyroid function 2 . Calcium, testosterone, PSA, & liver function 3 . Calcium, testosterone, PSA, liver function, glucose, & lipids 4 . CBC, testosterone, PSA, & thyroid level 22. Effects of estrogen include: 1. Regulation of the menstrual cycle 2. Maintenance of bone density by increasing bone reabsorption 3. Maintenance of the normal structure of the skin & blood vessels 4. A & C 5. All of the above 23. Absolute contraindications that clinicians must consider when initiating estrogen therapy include: 1. Undiagnosed dysfunctional uterine bleeding 2. Deep vein or arterial thromboemboli within the prior year 3. Endometriosis 4. 1 & 2 5. All of the above 24. Patients taking hormonal contraceptives & hormone replacement therapy need to take the drug daily at the same time to prevent: 1 .
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