Synercid arc17 anti anaerobic agents o clindamycin

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(Synercid) [Arc17]Anti-anaerobic agentsoClindamycinUsed to treat gram-positive and anaerobic bacterial infections
AGENTS10Binds to the 50S subunit of the bacterial ribosome and inhibits protein synthesis Dosage adjustment for liver impairmentCommon side effects: diarrhea and associated Clostridium difficile colitis [Arc17]oMetronidazoleRecognized for its antiprotozoal in Trichomonas vaginalisTreatment of choice for anaerobic infections, Clostridium difficile colitis, and as part of the treatment regimen for Helicobacter pylori-associated duodenal ulcersCompletely absorbed from GI tractDosage adjustment in hepatic impairmentInteracts with DNA causing strand breakage and results in protein synthesis inhibitionCommon side effects: nausea, vomiting, abdominal pain, and a metallic taste (Laureate Education, 2012)Miscellaneous antimicrobial agentsoChloramphenicolWide spectrum agent with activity against gram-positive, gram-negative, and anaerobic organismsUse limited due to toxicityBinds to the larger 50S subunit of the ribosome and inhibits bacterial protein synthesisUsed as an alternative treatment of bacterial meningitis when the patient has anaphylaxis to penicillinsCommon side effects: gray baby syndrome, blood dyscrasias, and optic neuritis [Arc17]Miscellaneous antimicrobial agentsoRifampinFirst-line treatment for tuberculosis Combined with other antibiotics to treat MRSASuppresses chain formation for RNA synthesis in susceptible bacteriaExtremely active against gram-positive cocci
AGENTS11Common side effects: nausea, vomiting, and diarrhea, headache, and fever, changes bodily fluids to a red-orange color (sweat, saliva, and tears) [Arc17]oNitrofurantoin Used for treating and preventing urinary tract infectionsMechanism of action is poorly understoodInhibits several bacterial enzymes causing impaired bacterial cell wall synthesisCommon side effects: nausea and vomiting [Lau12]Antiparasitic AgentsParasites live on or in the host. Human parasites include protozoa, flatworms, roundworms and ectoparasites such as ticks, fleas, lice, and mites. These cause diseases such as malaria, trichomoniasis, and Leishmaniasis. Antiparasitic agents are drugs used to treat parasitic diseases [Antnd1]. Antiviral AgentsAntiviral drugs are drugs used solely for treating infections caused by a virus. Antivirals are specific and may cover a wide range of pathogens. Antiviral drugs inhibit viruses development; they do not destroy the virus [Ani18]. Antifungal AgentsAntifungal agents are used to destroy or prevent the growth of fungi. Antifungal agents are one of the antibiotic groups. The most types of mycoses are processes such as athlete’s foot, ringworm, candidiasis (thrush), and systemic infections such as Cryptococci meningitis [Ani18].

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