Copyright 2017 Wolters Kluwer All Rights Reserved Topical Nasal Decongestants

Copyright 2017 wolters kluwer all rights reserved

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Copyright © 2017 Wolters Kluwer • All Rights ReservedTopical Nasal DecongestantsTopical Nasal DecongestantsActionsSympathomimeticAffects sympathetic nervous system to cause vasodilatationCausing less inflammation of the nasal membraneIndicationsRelieve the discomfort of nasal congestion that accompanies the common cold, sinusitis, and allergic rhinitis
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Copyright © 2017 Wolters Kluwer • All Rights ReservedTopical Nasal Decongestants (cont.)Topical Nasal Decongestants (cont.)PharmacokineticsGenerally not absorbed systemicallyAny portion of these topical decongestants that is absorbed is metabolized in the liver and excreted in the urineContraindicationsLesion or erosion in the mucous membranesCautionAny condition that might be exacerbated by sympathetic activity
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Copyright © 2017 Wolters Kluwer • All Rights ReservedTopical Nasal Decongestants (cont.)Topical Nasal Decongestants (cont.)Adverse Effects Local stinging and burningRebound congestionSympathomimetic effectsDrug-to-Drug InteractionsCyclopropane or halothane
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Copyright © 2017 Wolters Kluwer • All Rights ReservedNursing Considerations for Topical Nasal DecongestantsNursing Considerations for Topical Nasal DecongestantsAssess:History and Physical Exam and known allergy Glaucoma, hypertension, diabetes, thyroid disease, coronary disease, and prostate problemsOrientation and reflexes, VS and cardiac statusRespirations and adventitious lung soundsNasal mucous membrane and urinary statusPrototype : Tetrahydrozoline
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Copyright © 2017 Wolters Kluwer • All Rights ReservedOral DecongestantsOral DecongestantsDecrease nasal congestion related to the common cold, sinusitis, and allergic rhinitis- Pseudoephedrine (Triaminic Allergy Congestion, and many combination products)
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Copyright © 2017 Wolters Kluwer • All Rights ReservedOral DecongestantsOral DecongestantsActionsShrink the nasal mucous membrane by stimulating the alpha-adrenergic receptors in the nasal mucous membranesIndicationsPromotion of drainage in the sinuses and improving air flowPharmacokineticsWell absorbed, widely distributed in the bodyMetabolized in the liver and primarily excreted in urine
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Copyright © 2017 Wolters Kluwer • All Rights ReservedOral Decongestants (cont.)Oral Decongestants (cont.)ContraindicationsAny condition that might be exacerbated by sympathetic activityAdverse Effects Rebound congestionSympathetic effectsDrug-to-Drug InteractionsOTC products that contain pseudoephedrine; taking concurrently can cause serious side effects
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Copyright © 2017 Wolters Kluwer • All Rights ReservedNursing Considerations for Oral Decongestants Nursing Considerations for Oral Decongestants Assess:History and Physical Exam and known allergyPregnancy, lactation, hypertension, CADHyperthyroidism, diabetes mellitus, or prostate enlargementOrientation, reflexes, and affectVS and LSPrototype: Pseudoephedrine
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