and sweat gland high dose cardiac effects and dilation of blood vessels and

And sweat gland high dose cardiac effects and

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and sweat gland, high dose= cardiac effects and dilation of blood vessels and bronchi Scopolamine:similar to atropine, but can used for preanesthetic sedation, suppresses emesis and motion sickness, production of cycloplegia and mydriasis for ophthalmic proceduresGlycopyrrolate: reduces secretions, used for PUDIpratropium: used to treat asthma, COPD and rhinitis by inhalation or nasal spray
Oxybutynin: used for the treatment of overactive bladder, short half-life so frequent doses are needed for effective dosing Solifenacin:used to reduce episodes of urge incontinence, long half-life (50 hours), but can affect the QT interval at high dose and contraindicated in pt with liver impairment Benztropine: anti-tremor, used for Parkinson’sCholinesterase Inhibitors Prevent the breakdown of Ach by AchE so more Ach is available to activate a cholinergic receptorIndirectly activates receptors Clinical use, side/adverse effects, contraindications are the same as cholinergic agonistsDrugs to know Neostigmine: used for the management of myasthenia gravis (a condition caused by fluctuating muscle weakness and predisposition to chronic fatigue, anti-immune in which antibodies are created against nicotinic m receptors), also used to prevent neuromuscular blockage after surgery & return of spontaneous breathing, poorly absorbed PO & in the US only adm subq, IM, IV Physostigmine:drug of choice for treating poisoning by atropine and other drugs causing

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