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Metabolism can play a key role in determination of administration route. Because medications metabolizein different ways it is important to ensure that they are administered into the body in the proper ways. This will maximize their effectiveness and prevent the drug from being metabolized before it reaches its designated distribution site (Watkins, 2014). The final stage is excretion. This stage is of great significance because it removes the metabolized medications from the body as well any unmetabolized (unused) medication. This process mainly occurs in the kidneys. The liver, sweat and saliva glands, and lungs can also perform secretion but on much smaller levels. The overall functioning of the body can significantly impact the excretion process. Persons with impaired function of any of the organs involved in excretion can be at greater risk of medication toxicity (Watkins, 2014). 3. Discuss the difference between a side effect, a contraindication, and an adverse reaction to a medication.
a. Provide an example of a side effect, a contraindication, and an adverse reaction to a medication.2014).There are distinct differences between side effects, contraindications, and adverse reactions. Side effectsare generally mild and would not necessarily prevent a person from receiving a medication. Some examples of common side effects are nausea, vomiting, constipation, and environmental sensitivities. Many of these can be counteracted, or managed, through basic actions. Examples of such actions are: taking the medications before or after meals, at specific times, modifying physical activities, or limiting certain environmental exposures (Watkins, 2014). Adverse reactions have more severe consequences than side effects. These effects can even be potentially life threatening to the individual. While side effects can be expected and not necessarily prevent a medication from being prescribed or administered, this is not always true of adverse effects. In the event that an adverse effect is known to be possible efforts are made to limit the possibility. An example would be non-steroidal anti-inflammatory drugs (NSAIDs). These medications have the potentialto cause the adverse effect of gastrointestinal ulcers when taken on a long-term basis. The amount of themedication prescribed can be lowered to minimize this potential effect. Limiting the amount of time, the medication is taken is another alternative.