thus, altering the ability to absorb and use iron efficiently. IA associated with chronic infections such as AIDS, rheumatoid arthritis, lupus, and malignancies. Physical activity is usually limited due to low hemoglobin levels within tissue. The pathogenesis of anemia of inflammation and the regulation of iron absorption continues to cause unresolved hematology problems. Progress has been made on problems caused by hepcidin, an iron-regulatory hormone and a mediator of im- munity (Ganz, 2003). Also, due to inflammatory causes interfering with red blood cell produc- tion in the body, the ability to use stored iron and absorb iron from the diet is altered. Similarities and Differences IA is easily confused with iron-deficiency anemia because both forms of anemia levels of iron circulating in the blood are low and the clinical manifestations are identical. However, IA shows iron deficiency in marrow despite normal storage levels elsewhere when absorption of iron is altered (NIDDK, 2013). No treatment is needed unless symptoms become severe, with erythropoietin being a common treatment (Heuther & McCance, 2012). A lab test can measure ferritin levels in the blood, indicating the amount of iron stored in the body.
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- Spring '15
- Hemoglobin, Iron deficiency anemia, red blood cells