Physio Comprehensive SG 2015.docx

Sensations from internal organs but can include

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Sensations from internal organs but can include certain physiological processes, such as hunger, thirst, circulation. Pacinian corpuscle - A skin receptor cell type that detects vibration - Found throughout body in skin and muscle - Important for perception of texture - Mechanical stimuli delivered to the corpuscle produce a graded electrical potential w/amplitude that is directly proportional to the strength of the stimulus - AP occurs: o Mechanical stimulation deforms corpuscle o Deformation of the corpuscle stretches the tip of the axon o Allows Na+ to enter o Axon produces one or more AP Semicircular Canal - One of the three fluid-filled tubes in the inner ear - Part of the vestibular System - Detects angular acceleration Tonotopic Representation - A major organizational feature in auditory systems in which neurons are arranged as an orderly map of stimulus frequency, with cells responsive to high frequencies located at a distance from those responsive to low frequencies Essays Briefly Discuss Deficits of Verbally Controlled Movements: The Apraxias (9) (1) Apraxia: - Inability to begin and carry out skilled voluntary movement although there is no muscle paralysis (2) Callosal Apraxia: - Learned skilled movement w/right hand to verbal instruction - Cannot perform with left hand and can’t mimic - Due to lesion to corpus collosum - Prevents motor information from crossing to right hemisphere, hence left hand deficit (3) Constructional Apraxia - Can use objects properly and learn a skilled movement - However, can’t draw objects - Due to an inability to perceive and imagine geometric rx - Caused by injury to right parietal lobe - Can see this in poor parietal drawings and poor performance on BD (4) Sympathetic Apraxia:
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- Damage causes impairment to right arm/hand (full or partial) - Caused by damage to anterior left hemisphere - Can affect left arm too (5) Left Parietal Apraxia - Lesions of posterior left hemisphere, which impacts the area that keeps track of objects in the environment (i.e. knowing where things are around you) - Involves disability in both limbs (6) Ideomotor Apraxia: - Inability to complete simple motor activity on command (7) Ideational Apraxia: - Impairment in completing a sequence of tasks - With instruction of each step, able to complete (8) Limb Apraxia - Person has difficulty movement hands, arms, fingers in correct sequence (9) Occulomotor Apraxia - severe difficulty in voluntary steering visual gaze towards specific target Briefly Discuss The Frozen Addict pg. 331 2 - 1982: 6 ppl in CA were diagnosed w/Parkinsonism after having using synthesized drugs - NIH in collaboration with J. William Langston observed MPTP as cause and research its effects on primates o MPTP is a neurotoxin o Causes permanent sx of Parkinson’s disease by destroying dopaminergic neurons in substantia nigra of brain - Langston found injects of MPTP in monkeys resulted in Parkinsonian symptoms - Symptoms were reduced by L-Dopa - L-Dopa is a precursor to the neurotransmitter dopamine - Currently the drug-of-choice in tx of Parkinson’s -
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  • Fall '13
  • BrianHare

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