And when the matrix delivery system aka the chunk of polymer that contains drug

And when the matrix delivery system aka the chunk of

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chunk. And when the matrix delivery system – aka the ‘chunk’ of polymer that contains drug molecules dispersed through it – is placed near the target region for, there A question that you may want to ask yourself is … what is the difference between a matrix drug-delivery system vs. a reservoir drug-delivery system? What do you think? Hint: A noted limitation of the reservoir system is that drug molecules with large molecular weights or proteins (molecules with very high molecular weights!) may have more difficulty in dissolving into the surrounding polymer and in diffusing across through the enclosing polymer membrane. In such cases the matrix system is sometimes better because it allows the drug molecules and/or proteins already dissolved and dispersed throughout the polymer itself from the get-go, requiring only for drug to diffuse through the polymer to the external environment. Q: You are asked to design a delivery system that provides a constant rate of release of insulin. You want the system to release 1 mg of insulin per day. Will you use a matrix or a reservoir system? Make a list of the advantages and disadvantages of each design for this particular application. So let’s see here… from the question you glean that the desired rate of insulin release is a constant 1 mg per day. Which of the two: matrix OR reservoir system allows for a constant drug-release profile as a function of time? (by the way/for your edification: whenever you see the phrase “A as a function of B that means that the A is the y-axis (dependent variable) and B is the x-axis (independent variable)) Regarding drug delivery rates, which of the two do you think will produce a relatively more constant rate of drug release at steady-state? Hint: In the reservoir system, there is drug from the core that is in contact with the enclosing membrane trying to make it to the outside. And assuming for a good bit of
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